Results 51 to 60 of about 306,960 (301)

Shyness in Chinese preschool children: a latent class growth model

Humanities & Social Sciences Communications
Shyness is often linked to negative social adjustment, and children may exhibit various developmental patterns of social withdrawal behaviors at different stages.
Jingjing Zhu, Shuhui Xiang, Zhuyi Li, Yu Shen, Ye Tian, Yan Li   +5 more
doaj   +1 more source

Challenges in modelling the random structure correctly in growth mixture models and the impact this has on model mixtures [PDF]

, 2014
Lifecourse trajectories of clinical or anthropological attributes are useful for identifying how our early-life experiences influence later-life morbidity and mortality. Researchers often use growth mixture models (GMMs) to estimate such phenomena. It is
Bollen, Curran, D. L. Dahly, Duncan, E. Goodman, Goldstein, Kessler, Kline, L. D. Kubzansky, M. S. Gilthorpe, McArdle, Muthén, Y.-K. Tu   +12 more
core   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Trajectories of Lipids Profile and Incident Cardiovascular Disease Risk: A Longitudinal Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The association between low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol, and triglycerides with cardiovascular disease (CVD) has been well studied.
Alimu Dayimu, Chunxia Wang, Jiangbing Li, Bingbing Fan, Xiaokang Ji, Tao Zhang, Fuzhong Xue   +6 more
doaj   +1 more source

Factorization threshold models for scale-free networks generation [PDF]

, 2016
Many real networks such as the World Wide Web, financial, biological, citation and social networks have a power-law degree distribution. Networks with this feature are also called scale-free.
Artikov, Akmal, Dorodnykh, Aleksandr, Kashinskaya, Yana, Samosvat, Egor   +3 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

The heterogeneous life space trajectories and predictors in stroke patients: a cohort study

Frontiers in Neurology
ObjectiveThis study aimed to identify heterogeneous trajectories of life space among stroke patients and explore the predictors for different classes of life space.MethodsThis prospective cohort study assessed 210 stroke patients’ life space at baseline ...
Bei Yang, Bei Yang, Rui Xie, Siyuan Ge, Ruixue Tang, Kangyao Cheng, Yin Wang   +6 more
doaj   +1 more source

Trajectory of the development of caries in the permanent dentition of 12- to 16-year-old students based on a latent class growth model analysis in Liuyang

口腔疾病防治, 2023
Objective To explore the trajectory of the development of permanent caries in 12- to 16-year-old students in Liuyang and to provide a reference for the prevention and management of caries. Methods Primary and secondary school students who were registered
TAN Yangpeng, XU Xin, ZHANG Hong , XUN Han , YANG Tubao   +4 more
doaj   +1 more source

Modeling regional house prices [PDF]

, 2007
We develop a parsimonious panel model for quarterly regional house prices, for which both the cross-section and the time series dimension is large. The model allows for stochastic trends, cointegration, cross-equation correlations and, most importantly ...
Dijk, A. (Bram) van, Dijk, D.J.C. (Dick) van, Franses, Ph.H.B.F. (Philip Hans), Paap, R. (Richard)   +3 more
core