Results 61 to 70 of about 9,468,510 (297)
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Approximating a similarity matrix by a latent class model: A reappraisal of additive fuzzy clustering [PDF]
, 2009 Let Q be a given n×n square symmetric matrix of nonnegative elements between 0 and 1, similarities. Fuzzy clustering results in fuzzy assignment of individuals to K clusters.
Braak, C.J.F., ter +3 more
core +1 more source
The use of bayesian latent class cluster models to classify patterns of cognitive performance in healthy ageing. [PDF]
PLoS ONE, 2013 The main focus of this study is to illustrate the applicability of latent class analysis in the assessment of cognitive performance profiles during ageing.
Patrício Soares Costa +4 more
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Data Fit Comparison of Mixture Item Response Theory Models and Traditional Models
International Journal of Assessment Tools in Education, 2018 Thepurpose of this study is to determine the best IRT model [Rasch, 2PL, 3PL, 4PLand mixed IRT (2 and 3PL)] for the science and technology subtest of theTransition from Basic Education to Secondary Education (TEOG) exam, which is carriedout at national ...
Seher Yalçın
doaj +1 more source
Malaria Journal, 2022 Background Asymptomatic carriage of malaria parasites is common in high transmission intensity areas and confounds clinical case definitions for research studies.
Kennedy Mwai +10 more
doaj +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Unmodeled DIF in latent class analysis: Consequences for class enumeration
Methods in PsychologyThis paper builds upon previous research to investigate the effects of misspecified covariate relations in latent class analysis (LCA) using a Monte Carlo simulation.
Dina A.N. Arch, Karen Nylund-Gibson
doaj +1 more source
BMC Geriatrics, 2020 Background Fried’s Phenotype Model of Frailty (PMF) postulates that frailty is a syndrome. Features of a syndrome are a heterogeneous population that can be split into at least two classes, those presenting and those not presenting the syndrome ...
François Béland +11 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source