Results 61 to 70 of about 9,854,297 (301)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

The use of bayesian latent class cluster models to classify patterns of cognitive performance in healthy ageing. [PDF]

PLoS ONE, 2013
The main focus of this study is to illustrate the applicability of latent class analysis in the assessment of cognitive performance profiles during ageing.
Patrício Soares Costa, Nadine Correia Santos, Pedro Cunha, Joana Almeida Palha, Nuno Sousa   +4 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Unmodeled DIF in latent class analysis: Consequences for class enumeration

Methods in Psychology
This paper builds upon previous research to investigate the effects of misspecified covariate relations in latent class analysis (LCA) using a Monte Carlo simulation.
Dina A.N. Arch, Karen Nylund-Gibson
doaj   +1 more source

Data Fit Comparison of Mixture Item Response Theory Models and Traditional Models

International Journal of Assessment Tools in Education, 2018
Thepurpose of this study is to determine the best IRT model [Rasch, 2PL, 3PL, 4PLand mixed IRT (2 and 3PL)] for the science and technology subtest of theTransition from Basic Education to Secondary Education (TEOG) exam, which is carriedout at national ...
Seher Yalçın
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Revisiting the hypothesis of syndromic frailty: a cross-sectional study of the structural validity of the frailty phenotype

BMC Geriatrics, 2020
Background Fried’s Phenotype Model of Frailty (PMF) postulates that frailty is a syndrome. Features of a syndrome are a heterogeneous population that can be split into at least two classes, those presenting and those not presenting the syndrome ...
François Béland, Dominic Julien, Christina Wolfson, Howard Bergman, Pierrette Gaudreau, Claude Galand, John Fletcher, Maria-Victoria Zunzunegui, Bryna Shatenstein, Marie-Jeanne Kergoat, José A. Morais, Tamàs Fülöp   +11 more
doaj   +1 more source

Malaria attributable fractions with changing transmission intensity: Bayesian latent class vs logistic models

Malaria Journal, 2022
Background Asymptomatic carriage of malaria parasites is common in high transmission intensity areas and confounds clinical case definitions for research studies.
Kennedy Mwai, Irene Nkumama, Amos Thairu, James Mburu, Dennis Odera, Rinter Kimathi, Lydia Nyamako, James Tuju, Samson Kinyanjui, Eustasius Musenge, Faith Osier   +10 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Latent Class Model

, 2020
Application of latent class model for labelling astronomical images based on votes from vetters.
openaire   +2 more sources