Results 61 to 70 of about 11,069 (260)

Revisiting the hypothesis of syndromic frailty: a cross-sectional study of the structural validity of the frailty phenotype

BMC Geriatrics, 2020
Background Fried’s Phenotype Model of Frailty (PMF) postulates that frailty is a syndrome. Features of a syndrome are a heterogeneous population that can be split into at least two classes, those presenting and those not presenting the syndrome ...
François Béland, Dominic Julien, Christina Wolfson, Howard Bergman, Pierrette Gaudreau, Claude Galand, John Fletcher, Maria-Victoria Zunzunegui, Bryna Shatenstein, Marie-Jeanne Kergoat, José A. Morais, Tamàs Fülöp   +11 more
doaj   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

A Bayesian mixture model captures temporal and spatial structure of voting blocs within longitudinal referendum data

Political Science Research and Methods
The estimation of voting blocs is an important statistical inquiry in political science. However, the scope of these analyses is usually restricted to roll call data where individual votes are directly observed.
John O’Brien
doaj   +1 more source

Data Fit Comparison of Mixture Item Response Theory Models and Traditional Models

International Journal of Assessment Tools in Education, 2018
Thepurpose of this study is to determine the best IRT model [Rasch, 2PL, 3PL, 4PLand mixed IRT (2 and 3PL)] for the science and technology subtest of theTransition from Basic Education to Secondary Education (TEOG) exam, which is carriedout at national ...
Seher Yalçın
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Regularized Latent Class Analysis for Polytomous Item Responses: An Application to SPM-LS Data

Journal of Intelligence, 2020
The last series of Raven’s standard progressive matrices (SPM-LS) test was studied with respect to its psychometric properties in a series of recent papers. In this paper, the SPM-LS dataset is analyzed with regularized latent class models (RLCMs).
Alexander Robitzsch
doaj   +1 more source

A note on the identifiability of certain latent class models [PDF]

Wiering (2005, Statistics and Probability Letters, 75, 211-218) provides conditions for the identifiability of a class of latent models. Here we derive an alternative more general method of proving this result, which is based on standard identi ...
Cole, Diana J.
core  

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett, Syeda Amrah Hashmi, Amaan Qureshi, Heather Spader, Shayan Moosa, Ifrah Zawar   +5 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source