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Latent Mycobacterium tuberculosis Infection
New England Journal of Medicine, 2015The natural history of tuberculosis begins with the inhalation of Mycobacterium tuberculosis organisms; a period of bacterial replication and dissemination ensues, followed by immunologic containment of viable bacilli. The result of this process is asymptomatic latent tuberculosis infection, which is defined as a state of persistent bacterial viability,
Getahun, Haileyesus +3 more
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Treatment of latent tuberculosis infection
Seminars in Respiratory Infections, 2003Treatment of latent tuberculosis infection (LTBI) is considered an essential component of TB control programs in several industrialized countries and is being used in selected situations in developing countries. In 2000, the American Thoracic Society (ATS) and Centers for Disease Control and Prevention (CDC) published new recommendations on the ...
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Update on the Treatment of Tuberculosis and Latent Tuberculosis Infection
JAMA, 2005Tuberculosis (TB) has emerged as a global public health epidemic. Despite decreasing numbers of cases in the United States since 1992, TB remains a serious public health problem among certain patient populations and is highly prevalent in many urban areas.
Henry M, Blumberg +2 more
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Diagnostic Tests for Latent Tuberculosis Infection
Clinics in Chest Medicine, 2019Diagnosing latent tuberculosis (TB) infection (LTBI) is important globally for TB prevention. LTBI diagnosis requires a positive test for infection and negative evaluation for active disease. Current tests measure an immunologic response and include the tuberculin skin test (TST) and interferon-gamma release assays (IGRAs), T-SPOT.TB and QuantiFERON ...
Michelle K, Haas, Robert W, Belknap
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Latent Tuberculosis Infection and BCG Vaccination
Journal of Midwifery & Women's Health, 2005One third of the world's population is infected with Mycobacterium tuberculosis, and 5% to 10% of those infected will develop active disease. Identification and treatment of latent tuberculosis infection (LTBI) is an essential part of the public health strategy to control the spread of TB.
Lisa, Ross, Meredith, Goff
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Diagnosis of Latent Tuberculosis Infection
JAMA, 2005IN 2003, THE WORLD HEALTH ORGANIZATION REPORTED 8.8 million cases of tuberculosis (TB) worldwide, nearly half of them presenting with an infectious form of disease, and resulting in 1.7 million deaths from TB. Since TB transmission occurs before diagnosis in the index case, even when an optimal TB control program is in place, new and undiagnosed cases ...
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Advances in the Diagnosis of Latent Tuberculosis Infection
Seminars in Respiratory and Critical Care Medicine, 2013Accurate diagnosis of tuberculosis (TB) infection is an important component of tuberculosis control programs in many countries. Identification of persons with asymptomatic, or latent, tuberculosis infection allows for treatment of individuals at high risk for progressing to active disease so that the overall burden of tuberculosis disease is diminished.
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