Results 61 to 70 of about 6,143,323 (339)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

A Modification on Intra Class Correlation Estimation for Ordinal Scale Variable Using Latent Variable Model

open access: yesJournal of Biostatistics and Epidemiology, 2023
Background: A common way for computing test-retest reliability is Intra Class Correlation which was developed for continuous variables. But it widely used to assess test-retest reliability in questionnaires with Likert scales.
Samira Chaibakhsh, Asma Poorhosseingholi
doaj   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

A Bilateral Comparison of Fruit and Vegetable Consumption: United States and Canada

open access: yesJournal of Agricultural and Resource Economics, 2005
Many public programs promote diets rich in fruits and vegetables based on evidence of the derived health benefits. Still, produce consumption in the United States lags behind other nations, even its most culturally similar neighbor--Canada.
Timothy J. Richards, Paul M. Patterson
doaj   +1 more source

Recurrent Latent Variable Networks for Session-Based Recommendation

open access: yes, 2017
In this work, we attempt to ameliorate the impact of data sparsity in the context of session-based recommendation. Specifically, we seek to devise a machine learning mechanism capable of extracting subtle and complex underlying temporal dynamics in the ...
Bastien Frédéric   +12 more
core   +1 more source

Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung   +190 more
wiley   +1 more source

The Impact of Employer Attitude to Green Commuting Plans on Reducing Car Driving: A Mixed Method Analysis

open access: yesPromet (Zagreb), 2014
Reducing car trips and promoting green commuting modes are generally considered important solutions to reduce the increase of energy consumption and transportation CO2 emissions.
Chuan Ding   +3 more
doaj   +1 more source

Causal Effect Inference with Deep Latent-Variable Models [PDF]

open access: yes, 2017
Learning individual-level causal effects from observational data, such as inferring the most effective medication for a specific patient, is a problem of growing importance for policy makers.
Louizos, Christos   +5 more
core   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Modeling Latent Variable Uncertainty for Loss-based Learning [PDF]

open access: yes, 2012
We consider the problem of parameter estimation using weakly supervised datasets, where a training sample consists of the input and a partially specified annotation, which we refer to as the output.
Koller, Daphne   +2 more
core   +4 more sources

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