Results 141 to 150 of about 3,027,820 (357)

The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis [PDF]

open access: yes, 2012
Recent evidence highlights the peroxisome proliferator-activated receptors (PPARs) as critical neuroprotective factors in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). To gain new mechanistic insights into the role of
Maggi, Adriana   +8 more
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

A heuristic model of concurrent bi-lateral negotiations in incomplete information settings

open access: yes, 2003
Bi-lateral negotiations represent an important class of encounter in agent-based systems. To this end, this paper develops and evaluates a heuristic model that enables an agent to participate in multiple, concurrent bi-lateral encounters in competitive ...
Jennings, N. R.   +2 more
core  

Lateral diffusion processes in biomimetic polymer membranes [PDF]

open access: yes, 2015
Molecular self-assembly offers an important bottom-up approach to generate new materials with great potential for applications in nano-, life- and medical- sciences and engineering.
Itel, Fabian
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

The Interaction Between Railway Vehicle Dynamics And Track Lateral Alignment

open access: yes
This thesis examines the effect of vehicle dynamics on lateral deterioration of the track alignment. As rail traffic runs along a route, the forces imposed upon the track cause the ballast to settle, and hence the track geometry deteriorates.
Gong, Cencen
core  

An investigation into the effects of dystrophin on the lateral mobility of muscle membrane components. [PDF]

open access: yes, 1999
Dystrophin is the product of the Duchenne Muscular Dystrophy gene locus, whose absence results in progressive skeletal muscle breakdown. Despite considerable work on the localisation of dystrophin and its associated complex, its role in muscle function ...
Dutton, A.L., Dutton, Anna Louise
core  

Spinal Cord Atrophy Correlates With Disease Duration And Severity In Amyotrophic Lateral Sclerosis

open access: yes, 2015
Our objective was to investigate spinal cord (SC) atrophy in amyotrophic lateral sclerosis (ALS) patients, and to determine whether it correlates with clinical parameters.
De Andrade H.M.T.   +5 more
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi   +13 more
wiley   +1 more source

Service Parts Inventory Control with Lateral Transshipment that Takes Time

open access: yes
In equipment-intensive industries such as truck manufacturing, electronics manufacturing, photo copiers, and airliners, service parts are often slow moving items for which, in some cases, the transshipment time is not negligible.
Dekker, R., Yang, G.
core  

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