Results 71 to 80 of about 3,427,330 (298)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Metodología para medir la Capacidad de Producir Semillas de Calidad en Plantas élite de Café

open access: yesAgroecosistemas, 2022
La selección inadecuada de los granos de café para la obtención de semillas, genera la necesidad de desarrollar metodologías para evaluar e identificar los puntos óptimos para obtener plántulas de calidad.
Astudillo Herrera, Joselyn Elizabeth   +2 more
doaj  

Ultrasonographic Differentiation of Lateral Elbow Pain

open access: yesUltrasound International Open, 2016
Lateral elbow pain is often attributed to degenerative or posttraumatic impairment of the common extensor tendon. Ultrasonography assesses the soft tissue structures of the lateral elbow, allowing the differentiation between various underlying processes,
R. Obuchowicz, M. Bonczar
doaj   +1 more source

Theory of Myelin Coiling

open access: yes, 2005
A new model is proposed to explain coiling of myelins composed of fluid bilayers. This model allows the constituent bilayer cylinders of a myelin to be non-coaxial and the bilayer lateral tension to vary from bilayer to bilayer.
Bar-Ziv   +27 more
core   +1 more source

Ultrasound-Guided Lateral Femoral Cutaneous Nerve Cryoneurolysis for Analgesia in Patients With Burns. [PDF]

open access: yes, 2020
Autologous skin grafting from the thigh is frequently required for treatment of burns and is associated with intense pain at the donor site. Local anesthetic-based (LA) nerve blocks of the lateral femoral cutaneous nerve (LFCN) have been demonstrated to ...
Fiallo, Alfredo   +6 more
core  

Acoustic cues of palatalisation in plosive + lateral onset clusters [PDF]

open access: yes, 2009
Palatalisation of /l/ in obstruent + lateral onset clusters in the absence of a following palatal sound has received a considerable amount of attention from historical linguistics.
Martín Mota, Sidney, Müller, Daniela
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Análise das ações de escanteio e de lateral da equipe UFSM futsal na série ouro 2019

open access: yesRevista Brasileira de Futsal e Futebol, 2021
No Futsal a análise de desempenho vem ganhando cada vez mais importância, sendo a análise das ações de bola parada um dos fatores mais analisados pelas equipes de alto rendimento.
Airton dos Santos Alonço Junior   +1 more
doaj  

Surgical management of an accessory canal in a maxillary premolar: a case report [PDF]

open access: yesRestorative Dentistry & Endodontics, 2019
We report the surgical endodontic treatment of a maxillary first premolar with a lateral lesion that originated from an accessory canal. Although lesions originating from accessory canals frequently heal with simple conventional endodontic therapy, some ...
Hee-Jin Kim   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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