Results 1 to 10 of about 1,279,508 (285)

The central amygdala controls learning in the lateral amygdala. [PDF]

Nat Neurosci, 2017
Experience-driven synaptic plasticity in the lateral amygdala is thought to underlie the formation of associations between sensory stimuli and an ensuing threat.
Yu K, Ahrens S, Zhang X, Schiff H, Ramakrishnan C, Fenno L, Deisseroth K, Zhao F, Luo MH, Gong L, He M, Zhou P, Paninski L, Li B.   +13 more
europepmc   +6 more sources

Serotonergic control of GABAergic inhibition in the lateral amygdala. [PDF]

J Neurophysiol, 2020
Much evidence implicates the serotonergic regulation of the amygdala in anxiety. Thus, the present study was undertaken to characterize the influence of serotonin (5-HT) on principal neurons (PNs) of the rat lateral amygdala (LA), using whole-cell ...
Yamamoto R, Furuyama T, Sugai T, Ono M, Pare D, Kato N.   +5 more
europepmc   +4 more sources

A neuronal basis for fear discrimination in the lateral amygdala. [PDF]

Nat Commun, 2018
In the presence of new stimuli, it is crucial for survival to react with defensive responses in the presence of stimuli that resemble threats but also to not react with defensive behavior in response to new harmless stimuli.
Grosso A, Santoni G, Manassero E, Renna A, Sacchetti B.   +4 more
europepmc   +7 more sources

Hyperconnectivity of the lateral amygdala in long-term methamphetamine abstainers negatively correlated with withdrawal duration [PDF]

Frontiers in Pharmacology, 2023
Introduction: Several studies have reported structural and functional abnormalities of the amygdala caused by methamphetamine addiction. However, it is unknown whether abnormalities in amygdala function persist in long-term methamphetamine abstainers ...
Yifan Li, Xuhao Wang, Shucai Huang, Qiuping Huang, Ru Yang, Zhenjiang Liao, Xinxin Chen, Shuhong Lin, Yongyan Shi, Chenhan Wang, Ying Tang, Jingyue Hao, Jie Yang, Hongxian Shen   +13 more
doaj   +2 more sources

Amygdala pathology in amyotrophic lateral sclerosis and primary lateral sclerosis. [PDF]

Journal of the Neurological Sciences, 2020
Temporal lobe studies in motor neuron disease overwhelmingly focus on white matter alterations and cortical grey matter atrophy. Reports on amygdala involvement are conflicting and the amygdala is typically evaluated as single structure despite ...
Rangariroyashe Chipika, F. Christidi, E. Finegan, S. Li Hi Shing, M. McKenna, K. Chang, E. Karavasilis, Mark A. Doherty, Jennifer C. Hengeveld, A. Vajda, N. Pender, S. Hutchinson, C. Donaghy, R. Mclaughlin, O. Hardiman, P. Bede   +15 more
semanticscholar   +4 more sources

Synaptic and intrinsic plasticity within overlapping lateral amygdala ensembles following fear conditioning [PDF]

Frontiers in Cellular Neuroscience, 2023
IntroductionNew learning results in modulation of intrinsic plasticity in the underlying brain regions. Such changes in intrinsic plasticity can influence allocation and encoding of future memories such that new memories encoded during the period of ...
Megha Sehgal, Vanessa E. Ehlers, James R. Moyer, James R. Moyer   +3 more
doaj   +2 more sources

Synaptic correlates of associative fear memory in the lateral amygdala.

Neuron, 2021
Successful adaptation to the environment requires an accurate response to external threats by recalling specific memories. Memory formation and recall require engram cell activity and synaptic strengthening among activated neuronal ensembles. However, elucidation of the underlying neural substrates of associative fear memory has remained limited ...
D. Choi, Jooyoung Kim, Hoonwon Lee, Ji-il Kim, Yongmin Sung, Ja Eun Choi, S. Venkat, Pojeong Park, Hyunsu Jung, B. Kaang   +9 more
semanticscholar   +3 more sources

The entorhinal cortex modulates trace fear memory formation and neuroplasticity in the mouse lateral amygdala via cholecystokinin [PDF]

eLife, 2021
Although fear memory formation is essential for survival and fear-related mental disorders, the neural circuitry and mechanism are incompletely understood. Here, we utilized trace fear conditioning to study the formation of trace fear memory in mice.
Hemin Feng, Junfeng Su, Wei Fang, Xi Chen, Jufang He   +4 more
doaj   +2 more sources

Stress disrupts engram ensembles in lateral amygdala to generalize threat memory in mice. [PDF]

Cell
Stress induces aversive memory overgeneralization, a hallmark of many psychiatric disorders. Memories are encoded by a sparse ensemble of neurons active during an event (an engram ensemble).
Lesuis SL, Park S, Hoorn A, Rashid AJ, Mocle AJ, Salter EW, Vislavski S, Gray MT, Torelli AM, DeCristofaro A, Driever WPF, van der Stelt M, Zweifel LS, Collingridge GL, Lefebvre JL, Walters BJ, Frankland PW, Hill MN, Josselyn SA.   +18 more
europepmc   +2 more sources

Arc expression identifies the lateral amygdala fear memory trace [PDF]

Molecular Psychiatry, 2015
Memories are encoded within sparsely distributed neuronal ensembles. However, the defining cellular properties of neurons within a memory trace remain incompletely understood. Using a fluorescence-based Arc reporter, we were able to visually identify the
L. Gouty-Colomer, L. Gouty-Colomer, L. Gouty-Colomer, B. Hosseini, I. Marcelo, Jadwiga Schreiber, D. E. Slump, S. Yamaguchi, S. Yamaguchi, A. R. Houweling, D. Jaarsma, Y. Elgersma, S. Kushner   +12 more
semanticscholar   +4 more sources