Results 31 to 40 of about 876,155 (293)

Fear conditioning- and extinction-induced neuronal plasticity in the mouse amygdala [PDF]

open access: yes, 2009
Experience-dependent changes in behavior are mediated by long-term functional modifications in brain circuits. To study the underlying mechanisms, our lab is using classical auditory fear conditioning, a simple and robust form of associative learning. In
Ciocchi, Stéphane
core   +1 more source

Regional hypothalamic, amygdala, and midbrain periaqueductal gray matter recruitment during acute pain in awake humans: A 7-Tesla functional magnetic resonance imaging study

open access: yesNeuroImage, 2022
Over the past two decades, magnetic resonance imaging (MRI) studies have explored brain activation patterns during acute noxious stimuli. Whilst these human investigations have detailed changes in primarily cortical regions, they have generally not ...
Rebecca V Robertson   +6 more
doaj   +1 more source

Differential activation of anatomically defined neuronal subpopulations in the amygdala during fear conditioning and extinction [PDF]

open access: yes, 2009
The amygdala is a key structure of the neuronal circuitry mediating expression and extinction of conditioned fear. However, fear memories are thought to be encoded in a larger network comprising the medial prefrontal cortex (mPFC) and the ...
Senn, Verena
core   +1 more source

A recurrent network in the lateral amygdala: a mechanism for coincidence detection [PDF]

open access: yesFrontiers in Neural Circuits, 2008
Synaptic changes at sensory inputs to the dorsal nucleus of the lateral amygdala (LAd) play a key role in the acquisition and storage of associative fear memory. However, neither the temporal nor spatial architecture of the LAd network response to sensory signals is understood. We developed a method for the elucidation of network behavior.
Johnson, Luke R.   +8 more
openaire   +6 more sources

Predominant synaptic potentiation and activation in the right central amygdala are independent of bilateral parabrachial activation in the hemilateral trigeminal inflammatory pain model of rats

open access: yesMolecular Pain, 2018
Nociceptive signals originating in the periphery are conveyed to the brain through specific afferent and ascending pathways. The spino-(trigemino-)parabrachio-amygdaloid pathway is one of the principal pathways mediating signals from nociception-specific
Yuta Miyazawa   +3 more
doaj   +1 more source

Thalamic, hippocampal and basal ganglia pathology in primary lateral sclerosis and amyotrophic lateral sclerosis: Evidence from quantitative imaging data

open access: yesData in Brief, 2020
Primary lateral sclerosis and amyotrophic lateral sclerosis are primarily associated with motor cortex and corticospinal tract pathology. A standardised, prospective, single-centre neuroimaging protocol was used to characterise thalamic, hippocampal and ...
Eoin Finegan   +11 more
doaj   +1 more source

Neuropeptide S-mediated facilitation of synaptic transmission enforces subthreshold theta oscillations within the lateral amygdala. [PDF]

open access: yesPLoS ONE, 2011
The neuropeptide S (NPS) receptor system modulates neuronal circuit activity in the amygdala in conjunction with fear, anxiety and the expression and extinction of previously acquired fear memories.
Susanne Meis   +2 more
doaj   +1 more source

Modulating anxiety with extrasynaptic inhibition [PDF]

open access: yes, 2014
Traumatic experiences and stress can lead to complex behavioral adaptations, including increased levels of anxiety and fear generalization. The neuronal mechanisms underlying such maladaptive behavioral changes are, however, poorly understood.
Botta, Paolo
core   +1 more source

Amount of fear extinction changes its underlying mechanisms

open access: yeseLife, 2017
There has been a longstanding debate on whether original fear memory is inhibited or erased after extinction. One possibility that reconciles this uncertainty is that the inhibition and erasure mechanisms are engaged in different phases (early or late ...
Bobae An   +5 more
doaj   +1 more source

The α1 subunit of the GABA(A) receptor modulates fear learning and plasticity in the lateral amygdala

open access: yesFrontiers in Behavioral Neuroscience, 2009
Synaptic plasticity in the amydgala is essential for emotional learning. Fear conditioning, for example, depends on changes in excitatory transmission that occur following NMDA receptor activation and AMPA receptor modification in this region. The role
Brian J Wiltgen   +17 more
doaj   +1 more source

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