Results 1 to 10 of about 120,536 (119)
Activity-dependent phosphorylation of CDYL by CDK5 regulates fear memory in mice [PDF]
Translational PsychiatryFear memory is crucial for animals to effectively respond to dynamic environments and survive dangerous stimuli. However, aberrant fear memory contributes to various psychiatric disorders, such as post-traumatic stress disorder (PTSD).
Na-Yun Lyu +6 more
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Frontiers in Molecular Neuroscience, 2021 Abnormality of fear memory is one of the important pathogenic factors leading to post-traumatic stress disorder (PTSD), anxiety disorder, and other mental disorders.
Jinfeng Su +10 more
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A critical role of hippocampus for formation of remote cued fear memory
Molecular Brain, 2020 A unique feature of fear memory is its persistence that is highly relevant to fear and anxiety-related mental disorders. Recurrent reactivation of neural representations acquired from a traumatic event is thought to contribute to the indelibility of fear
Jung-Pyo Oh, Jin-Hee Han
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EphrinA4 mimetic peptide impairs fear conditioning memory reconsolidation in lateral amygdala
Scientific Reports, 2022 Fear memory may undergo a process after memory reactivation called reconsolidation. To examine the roles of ephrinA4 in fear memory reconsolidation an inhibitory ephrinA4 mimetic peptide (pep-ephrinA4), that targets the EphA binding site and inhibits ...
Ron Mana +3 more
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Reversible plasticity of fear memory-encoding amygdala synaptic circuits even after fear memory consolidation. [PDF]
PLoS ONE, 2011 It is generally believed that after memory consolidation, memory-encoding synaptic circuits are persistently modified and become less plastic. This, however, may hinder the remaining capacity of information storage in a given neural circuit.
Ingie Hong +14 more
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Frontiers in Behavioral Neuroscience, 2021 Reactivation of consolidated memories can induce a labile period, in which these reactivated memories might be susceptible to change and need reconsolidation.
Wei Chen +10 more
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Anterior basolateral amygdala neurons comprise a remote fear memory engram
Frontiers in Neural Circuits, 2023 IntroductionThreatening environmental cues often generate enduring fear memories, but how these are formed and stored remains actively investigated. Recall of a recent fear memory is thought to reflect reactivation of neurons, in multiple brain regions ...
Robert J. Hammack +6 more
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Validation of the Fear and Avoidance of Memory Loss scale in community‐based older adults
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2023 Introduction Alzheimer's disease and related dementias (ADRD) are among the most feared conditions. However, research around ADRD‐specific fear and avoidance behaviors is lacking.
Francesca R. Farina +9 more
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Nck1 activity in lateral amygdala regulates long-term fear memory formation
Translational Psychiatry, 2022 Fear conditioning leads to long-term fear memory formation and is a model for studying fear-related psychopathological conditions such as phobias and post-traumatic stress disorder.
Or Ilovich +4 more
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iScience, 2023 Summary: The organization of fear memory involves the participation of multiple brain regions. However, it is largely unknown how fear memory is formed, which circuit pathways are used for “printing” memory engrams across brain regions, and the role of ...
Ilaria Bertocchi +14 more
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