Results 41 to 50 of about 2,304,658 (297)

Beta-adrenergic receptors in the lateral nucleus of the amygdala contribute to the acquisition but not the consolidation of auditory fear conditioning

Frontiers in Behavioral Neuroscience, 2010
Beta-adrenergic receptors (βARs) have long been associated with fear disorders and with learning and memory. However, the contribution of these receptors to Pavlovian fear conditioning, a leading behavioral model for studying fear learning and ...
David E A Bush, Ellen M Caparosa, Anna Gekker, Joseph LeDoux, Joseph LeDoux   +4 more
doaj   +1 more source

A ventral hippocampus-basolateral amygdala circuit regulates the unconditioned stimulus retrieval-induced reconsolidation of remote fear memory

Journal of Advanced Research
Introduction: Memory is retrieved and updated during reconsolidation, which provides a potential target for therapeutic intervention. Reconsolidation blockade following unconditioned stimulus (US) retrieval has shown increasing promise in disrupting ...
Dan Guo, Zhong Wang, Fanglin Liu, Wenhao Chen, Xuejiao Gao, Shihao Huang, Serik Tabarak, Yuan Yao, Shiya Zhang, Jie Shi, Lin Lu, Ying Han   +11 more
doaj   +1 more source

Activation of astrocytes in hippocampus decreases fear memory through adenosine A1 receptors

eLife, 2020
Astrocytes respond to and regulate neuronal activity, yet their role in mammalian behavior remains incompletely understood. Especially unclear is whether, and if so how, astrocyte activity regulates contextual fear memory, the dysregulation of which ...
Yulan Li, Lixuan Li, Jintao Wu, Zhenggang Zhu, Xiang Feng, Liming Qin, Yuwei Zhu, Li Sun, Yijun Liu, Zilong Qiu, Shumin Duan, Yan-Qin Yu   +11 more
doaj   +1 more source

Hippocampal Administration of Levothyroxine Impairs Contextual Fear Memory Consolidation in Rats

Frontiers in Cellular Neuroscience, 2017
Thyroid hormone (TH) receptors are highly distributed in the hippocampus, which plays a vital role in memory processes. However, how THs are involved in the different stages of memory process is little known.
Dafu Yu, Dafu Yu, Heng Zhou, Heng Zhou, Lin Zou, Yong Jiang, Xiaoqun Wu, Lizhu Jiang, Lizhu Jiang, Qixin Zhou, Yuexiong Yang, Lin Xu, Rongrong Mao   +12 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Deficiency of the RIβ subunit of protein kinase A causes body tremor and impaired fear conditioning memory in rats [PDF]

, 2021
The RIβ subunit of cAMP-dependent protein kinase (PKA), encoded by Prkar1b, is a neuronal isoform of the type I regulatory subunit of PKA. Mice lacking the RIβ subunit exhibit normal long-term potentiation (LTP) in the Schaffer collateral pathway of the ...
Hieu, Hoang Trung, SHIRASUNA, Koumei, HIRATA, Yoshiki, KURAMOTO, Takashi, KUWAMURA, Mitsuru, NAKAO, Akito, YOSHIHARA, Toru, HAYASHIDA, Katsumi, ASANO, Masahide, NAKAGAWA, Yuki, MORI, Yasuo, KANEKO, Takehito   +11 more
core  

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Adult-onset hypothyroidism enhances fear memory and upregulates mineralocorticoid and glucocorticoid receptors in the amygdala.

PLoS ONE, 2011
Hypothyroidism is the most common hormonal disease in adults, which is frequently accompanied by learning and memory impairments and emotional disorders.
Ana Montero-Pedrazuela, Iván Fernández-Lamo, María Alieva, Inmaculada Pereda-Pérez, César Venero, Ana Guadaño-Ferraz   +5 more
doaj   +1 more source

Optogenetic stimulation of a hippocampal engram activates fear memory recall [PDF]

, 2011
A specific memory is thought to be encoded by a sparse population of neurons. These neurons can be tagged during learning for subsequent identification3 and manipulation.
Karl Deisseroth, Liu, Xu, Tonegawa, Susumu, Deisseroth, Karl, Steve Ramirez, Pang, Petti, Ramirez Moreno, Steve, Corey B. Puryear, Govindarajan, Arvind, Arvind Govindarajan, Puryear, Corey, Susumu Tonegawa, Petti T. Pang, Xu Liu   +13 more
core   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source