A ventral hippocampus-basolateral amygdala circuit regulates the unconditioned stimulus retrieval-induced reconsolidation of remote fear memory. [PDF]
J Adv ResIntroduction: Memory is retrieved and updated during reconsolidation, which provides a potential target for therapeutic intervention. Reconsolidation blockade following unconditioned stimulus (US) retrieval has shown increasing promise in disrupting ...
Guo D +11 more
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Hippocampal ERK2 dimerization regulates inhibitory avoidance memory reconsolidation and synaptic plasticity. [PDF]
iScienceSummary: Extensive research has examined extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation in memory and synaptic plasticity, yet the mechanisms linking ERK activity to memory stabilization remain unclear.
Ojea Ramos S +9 more
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The ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation. [PDF]
Transl PsychiatryAddictive drugs engage molecular pathways of associative learning and memory. Drug craving triggered by cues that were once associated with drug intoxication contributes to continued drug-seeking behaviors.
Caban Rivera C +10 more
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Linking new information to a reactivated memory requires consolidation and not reconsolidation mechanisms. [PDF]
PLoS Biology, 2005 A new memory is initially labile and becomes stabilized through a process of consolidation, which depends on gene expression. Stable memories, however, can again become labile if reactivated by recall and require another phase of protein synthesis in ...
Sophie Tronel +2 more
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Translational Psychiatry, 2021 The majority of smokers relapse even after successfully quitting because of the craving to smoking after unexpectedly re-exposed to smoking-related cues.
Xiao Lin +15 more
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Translational Psychiatry, 2023 Memory reconsolidation refers to the process by which the consolidated memory was restored after reactivation (RA). Memory trace becomes labile after reactivation and inhibition of memory reconsolidation may disrupt or update the original memory trace ...
Rui Chang +8 more
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Is Reconsolidation a General Property of Memory?
Frontiers in Human Neuroscience, 2021 Memory reconsolidation holds great hope for memory modification approaches and clinical treatments of mental disorders associated with maladaptive memories.
Gayoung Kim +4 more
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Disruption of Memory Reconsolidation Erases a Fear Memory Trace in the Human Amygdala: An 18-Month Follow-Up. [PDF]
PLoS ONE, 2015 Fear memories can be attenuated by reactivation followed by disrupted reconsolidation. Using functional magnetic resonance imaging we recently showed that reactivation and reconsolidation of a conditioned fear memory trace in the basolateral amygdala ...
Johannes Björkstrand +6 more
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Modulation of memory reconsolidation by adjacent novel tasks: timing defines the nature of change
Communications Biology, 2023 Reconsolidation turns memories into a responsive state that allows their modulation until they stabilize again. This phenomenon attracted remarkable attention due to its potential impact on therapeutics and education.
Matías Nicolás Schroeder +3 more
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Recall and reconsolidation of contextual fear memory: differential control by ERK and Zif268 expression dosage. [PDF]
PLoS ONE, 2013 Compelling evidence points to the existence of independent cellular processes involved in the consolidation and reconsolidation of memory. For instance, a double dissociation has been reported between hippocampal Extracellular-Regulated Kinase-1/2 (ERK1 ...
Antoine Besnard +2 more
doaj +1 more source