Results 1 to 10 of about 8,759 (205)
A model of synaptic reconsolidation [PDF]
Reconsolidation of memories has mostly been studied at the behavioral and molecular level. Here, we put forward a simple extension of existing computational models of synaptic consolidation to capture hippocampal slice experiments that have been ...
David B. Kastner +4 more
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The Mechanisms and Boundary Conditions of Drug Memory Reconsolidation
Drug addiction can be seen as a disorder of maladaptive learning characterized by relapse. Therefore, disrupting drug-related memories could be an approach to improving therapies for addiction.
Liangpei Chen +9 more
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Although reconsolidation-based interventions constitute a promising new avenue to treating fear and anxieties disorders, the success of the intervention is not guaranteed.
A. M. V. Gerlicher +2 more
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Repeated labilization-reconsolidation processes strengthen declarative memory in humans. [PDF]
The idea that memories are immutable after consolidation has been challenged. Several reports have shown that after the presentation of a specific reminder, reactivated old memories become labile and again susceptible to amnesic agents.
Cecilia Forcato +2 more
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Differential involvement of brain-derived neurotrophic factor in reconsolidation and consolidation of conditioned taste aversion memory. [PDF]
Consolidated memory can re-enter states of transient instability following reactivation, which is referred to as reconsolidation, and the exact molecular mechanisms underlying this process remain unexplored. Brain-derived neurotrophic factor (BDNF) plays
Yue Wang +6 more
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Over the Edge: Extending the duration of a reconsolidation intervention for spider fear
Pharmacologically disrupting fear memory reconsolidation dramatically reduces fear behaviour. For example, 2–3 min of tarantula exposure followed by 40 mg of propranolol HCl (i.e., a reconsolidation intervention) abruptly decreased spider avoidance, an ...
Anna I. Filmer +4 more
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Memory reconsolidation in aversive and appetitive settings
Memory reconsolidation has been observed across species and in a number of behavioural paradigms. The majority of memory reconsolidation studies have been carried out in pavlovian fear conditioning and other aversive memory settings, with potential ...
Amy Claire Reichelt +2 more
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Recent research on altering threat memory has focused on a reconsolidation window. During reconsolidation, threat memories are retrieved and become labile.
Erin E. Koffman +10 more
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Memory consolidation is the process underlying the stabilization of labile short-term memory and the generation of long-term memory for persistent memory storage. The retrieval of contextual fear memory induces two distinct and opposite memory processes:
Yu Arihara, Yudai Fukuyama, Satoshi Kida
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Translational research highlights the potential of novel 'memory consolidation/reconsolidation therapies' to treat re-experiencing symptoms and post-traumatic stress disorder (PTSD).
Laurence Astill Wright +3 more
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