Is Reconsolidation a General Property of Memory?
Frontiers in Human Neuroscience, 2021 Memory reconsolidation holds great hope for memory modification approaches and clinical treatments of mental disorders associated with maladaptive memories.
Gayoung Kim +4 more
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Modulation of memory reconsolidation by adjacent novel tasks: timing defines the nature of change [PDF]
Communications Biology, 2023 Reconsolidation turns memories into a responsive state that allows their modulation until they stabilize again. This phenomenon attracted remarkable attention due to its potential impact on therapeutics and education.
Matías Nicolás Schroeder +3 more
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The hippocampal FTO-BDNF-TrkB pathway is required for novel object recognition memory reconsolidation in mice [PDF]
Translational Psychiatry, 2023 Memory reconsolidation refers to the process by which the consolidated memory was restored after reactivation (RA). Memory trace becomes labile after reactivation and inhibition of memory reconsolidation may disrupt or update the original memory trace ...
Rui Chang +8 more
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The Mechanisms and Boundary Conditions of Drug Memory Reconsolidation [PDF]
Frontiers in Neuroscience, 2021 Drug addiction can be seen as a disorder of maladaptive learning characterized by relapse. Therefore, disrupting drug-related memories could be an approach to improving therapies for addiction.
Liangpei Chen +9 more
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EphrinA4 mimetic peptide impairs fear conditioning memory reconsolidation in lateral amygdala [PDF]
Scientific Reports, 2022 Fear memory may undergo a process after memory reactivation called reconsolidation. To examine the roles of ephrinA4 in fear memory reconsolidation an inhibitory ephrinA4 mimetic peptide (pep-ephrinA4), that targets the EphA binding site and inhibits ...
Ron Mana +3 more
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Hippocampal ERK2 dimerization regulates inhibitory avoidance memory reconsolidation and synaptic plasticity [PDF]
iScienceSummary: Extensive research has examined extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation in memory and synaptic plasticity, yet the mechanisms linking ERK activity to memory stabilization remain unclear.
Santiago Ojea Ramos +9 more
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Differential effects of cannabidiol on inhibitory avoidance memory reconsolidation and consolidation are associated with distinct hippocampal proBDNF and BDNF signaling profiles [PDF]
Frontiers in NeuroscienceIntroductionCannabidiol (CBD), a major non-psychoactive constituent of Cannabis sativa, exerts pleiotropic effects, including antipsychotic, anxiolytic, and neuroprotective properties, with low toxicity and minimal euphoric effects. Previous studies have
Wen Dai +2 more
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The ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation [PDF]
Translational PsychiatryAddictive drugs engage molecular pathways of associative learning and memory. Drug craving triggered by cues that were once associated with drug intoxication contributes to continued drug-seeking behaviors.
Carolina Caban Rivera +10 more
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Memory reconsolidation impairment by amyloid beta (1–42) and its prevention by non-competitive antagonists of NMDA receptors [PDF]
Frontiers in Cellular NeuroscienceIn a healthy brain, the reactivation of memories under conditions of novelty leads to their labilization and subsequent reconsolidation. However, if plasticity of the nervous system is reduced reconsolidation mechanisms may be disrupted, leading to ...
A. A. Tiunova +3 more
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Brain Research Bulletin, 2023 Memory consolidation is the process underlying the stabilization of labile short-term memory and the generation of long-term memory for persistent memory storage. The retrieval of contextual fear memory induces two distinct and opposite memory processes:
Yu Arihara, Yudai Fukuyama, Satoshi Kida
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