Results 1 to 10 of about 454 (129)

Consolidation, reconsolidation, and extinction of contextual fear memory depend on de novo protein synthesis in the locus coeruleus

open access: yesBrain Research Bulletin, 2023
Memory consolidation is the process underlying the stabilization of labile short-term memory and the generation of long-term memory for persistent memory storage. The retrieval of contextual fear memory induces two distinct and opposite memory processes:
Yu Arihara, Yudai Fukuyama, Satoshi Kida
doaj   +1 more source

Is Reconsolidation a General Property of Memory?

open access: yesFrontiers in Human Neuroscience, 2021
Memory reconsolidation holds great hope for memory modification approaches and clinical treatments of mental disorders associated with maladaptive memories.
Gayoung Kim   +4 more
doaj   +1 more source

The hippocampal FTO-BDNF-TrkB pathway is required for novel object recognition memory reconsolidation in mice

open access: yesTranslational Psychiatry, 2023
Memory reconsolidation refers to the process by which the consolidated memory was restored after reactivation (RA). Memory trace becomes labile after reactivation and inhibition of memory reconsolidation may disrupt or update the original memory trace ...
Rui Chang   +8 more
doaj   +1 more source

Differential involvement of brain-derived neurotrophic factor in reconsolidation and consolidation of conditioned taste aversion memory. [PDF]

open access: yesPLoS ONE, 2012
Consolidated memory can re-enter states of transient instability following reactivation, which is referred to as reconsolidation, and the exact molecular mechanisms underlying this process remain unexplored. Brain-derived neurotrophic factor (BDNF) plays
Yue Wang   +6 more
doaj   +1 more source

Repeated labilization-reconsolidation processes strengthen declarative memory in humans. [PDF]

open access: yesPLoS ONE, 2011
The idea that memories are immutable after consolidation has been challenged. Several reports have shown that after the presentation of a specific reminder, reactivated old memories become labile and again susceptible to amnesic agents.
Cecilia Forcato   +2 more
doaj   +1 more source

The Mechanisms and Boundary Conditions of Drug Memory Reconsolidation

open access: yesFrontiers in Neuroscience, 2021
Drug addiction can be seen as a disorder of maladaptive learning characterized by relapse. Therefore, disrupting drug-related memories could be an approach to improving therapies for addiction.
Liangpei Chen   +9 more
doaj   +1 more source

Disruption of Memory Reconsolidation Erases a Fear Memory Trace in the Human Amygdala: An 18-Month Follow-Up. [PDF]

open access: yesPLoS ONE, 2015
Fear memories can be attenuated by reactivation followed by disrupted reconsolidation. Using functional magnetic resonance imaging we recently showed that reactivation and reconsolidation of a conditioned fear memory trace in the basolateral amygdala ...
Johannes Björkstrand   +6 more
doaj   +1 more source

Recall and reconsolidation of contextual fear memory: differential control by ERK and Zif268 expression dosage. [PDF]

open access: yesPLoS ONE, 2013
Compelling evidence points to the existence of independent cellular processes involved in the consolidation and reconsolidation of memory. For instance, a double dissociation has been reported between hippocampal Extracellular-Regulated Kinase-1/2 (ERK1 ...
Antoine Besnard   +2 more
doaj   +1 more source

Acid-sensing ion channel 1a regulates the specificity of reconsolidation of conditioned threat responses

open access: yesJCI Insight, 2022
Recent research on altering threat memory has focused on a reconsolidation window. During reconsolidation, threat memories are retrieved and become labile.
Erin E. Koffman   +10 more
doaj   +1 more source

Memory reconsolidation in aversive and appetitive settings

open access: yesFrontiers in Behavioral Neuroscience, 2013
Memory reconsolidation has been observed across species and in a number of behavioural paradigms. The majority of memory reconsolidation studies have been carried out in pavlovian fear conditioning and other aversive memory settings, with potential ...
Amy Claire Reichelt   +2 more
doaj   +1 more source

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