Results 31 to 40 of about 1,728,317 (155)

Extracellular signal-regulated kinase in the basolateral amygdala is required for reconsolidation of heroin-associated memory

Frontiers in Molecular Neuroscience, 2022
Reconsolidation of heroin-associated memory is an independent memory process that occurs following retrieval, which is essential for the sustained capacity of an associative drug stimulus to precipitate heroin-seeking.
Haoyu Li, Haoyu Li, Haoyu Li, Ting Hu, Ting Hu, Ting Hu, Yanghui Zhang, Zijin Zhao, Zijin Zhao, Zijin Zhao, Qing Liu, Qing Liu, Qing Liu, Zihua Chen, Zihua Chen, Si Chen, Si Chen, Si Chen   +17 more
doaj   +1 more source

Retrieval cues that trigger reconsolidation of associative fear memory are not necessarily an exact replica of the original learning experience

Frontiers in Behavioral Neuroscience, 2015
Disrupting the process of memory reconsolidation may point to a novel therapeutic strategy for the permanent reduction of fear in patients suffering from anxiety disorders.
Marieke eSoeter, Merel eKindt
doaj   +1 more source

Inhibition of Glycogen Synthase Kinase 3β Activity in the Basolateral Amygdala Disrupts Reconsolidation and Attenuates Heroin Relapse

Frontiers in Molecular Neuroscience, 2022
Exposure to a heroin-associated conditioned stimulus can reactivate drug reward memory, trigger drug cravings, and induce relapse in heroin addicts. The amygdala, a brain region related to emotions and motivation, is involved in processing rewarding ...
Yuanyang Xie, Yuanyang Xie, Yingfan Zhang, Ting Hu, Ting Hu, Zijin Zhao, Zijin Zhao, Qing Liu, Qing Liu, Haoyu Li, Haoyu Li   +10 more
doaj   +1 more source

Memory Reconsolidation: Making Predictions Better

, 2022
Memory reconsolidation refers to the phenomenon whereby a previously consolidated memory, i.e., one that is resistant to interference or disruption, becomes labile due to reactivation, initiating a short window during which that memory can be modified ...
Per Benjamin Sederberg, Lynn Nadel
core   +1 more source

Modeling reconsolidation in kernel associative memory. [PDF]

PLoS ONE, 2013
Memory reconsolidation is a central process enabling adaptive memory and the perception of a constantly changing reality. It causes memories to be strengthened, weakened or changed following their recall.
Dimitri Nowicki, Patrick Verga, Hava Siegelmann   +2 more
doaj   +1 more source

A ventral hippocampus-basolateral amygdala circuit regulates the unconditioned stimulus retrieval-induced reconsolidation of remote fear memory

Journal of Advanced Research
Introduction: Memory is retrieved and updated during reconsolidation, which provides a potential target for therapeutic intervention. Reconsolidation blockade following unconditioned stimulus (US) retrieval has shown increasing promise in disrupting ...
Dan Guo, Zhong Wang, Fanglin Liu, Wenhao Chen, Xuejiao Gao, Shihao Huang, Serik Tabarak, Yuan Yao, Shiya Zhang, Jie Shi, Lin Lu, Ying Han   +11 more
doaj   +1 more source

Better, worse, or different than expected: on the role of value and identity prediction errors in fear memory reactivation

Scientific Reports, 2022
Although reconsolidation-based interventions constitute a promising new avenue to treating fear and anxieties disorders, the success of the intervention is not guaranteed.
A. M. V. Gerlicher, S. A. Verweij, M. Kindt   +2 more
doaj   +1 more source

Enhancement of fear memory by retrieval through reconsolidation

eLife, 2014
Memory retrieval is considered to have roles in memory enhancement. Recently, memory reconsolidation was suggested to reinforce or integrate new information into reactivated memory.
Hotaka Fukushima, Yue Zhang, Georgia Archbold, Rie Ishikawa, Karim Nader, Satoshi Kida   +5 more
doaj   +1 more source

Impairing of Serotonin Synthesis by P-Chlorphenylanine Prevents the Forgetting of Contextual Memory After Reminder and the Protein Synthesis Inhibition

Frontiers in Pharmacology, 2018
HIGHLIGHTSThe injection of p-chlorophenylalanine, specific blocker of 5-HT synthesis 3 days before reminder with anisomycin administration prevented forgetting.It is known that the reminder cause reactivation of the long-term memory and it leads to ...
Irina B. Deryabina, Lyudmila N. Muranova, Vyatcheslav V. Andrianov, Khalil L. Gainutdinov   +3 more
doaj   +1 more source

Disrupting reconsolidation by PKA inhibitor in BLA reduces heroin-seeking behavior

Frontiers in Cellular Neuroscience, 2022
Drug abuse is considered a maladaptive pathology of emotional memory and is associated with craving and relapse induced by drug-associated stimuli or drugs.
Yanghui Zhang, Haoxian Li, Ting Hu, Ting Hu, Zijin Zhao, Zijin Zhao, Qing Liu, Qing Liu, Haoyu Li, Haoyu Li   +9 more
doaj   +1 more source