Results 31 to 40 of about 454 (129)

Modulation of memory reconsolidation by adjacent novel tasks: timing defines the nature of change

Communications Biology, 2023
Reconsolidation turns memories into a responsive state that allows their modulation until they stabilize again. This phenomenon attracted remarkable attention due to its potential impact on therapeutics and education.
Matías Nicolás Schroeder, Camila L. Fullio, Fabricio Ballarini, Diego Moncada   +3 more
doaj   +1 more source

Behavioural memory reconsolidation of food and fear memories [PDF]

Nature Communications, 2011
The reactivation of a memory through retrieval can render it subject to disruption or modification through the process of memory reconsolidation. In both humans and rodents, briefly reactivating a fear memory results in effective erasure by subsequent extinction training.
Flavell, Charlotte R., Barber, David J., Lee, Jonathan L. C.   +2 more
openaire   +2 more sources

Impairing of Serotonin Synthesis by P-Chlorphenylanine Prevents the Forgetting of Contextual Memory After Reminder and the Protein Synthesis Inhibition

Frontiers in Pharmacology, 2018
HIGHLIGHTSThe injection of p-chlorophenylalanine, specific blocker of 5-HT synthesis 3 days before reminder with anisomycin administration prevented forgetting.It is known that the reminder cause reactivation of the long-term memory and it leads to ...
Irina B. Deryabina, Lyudmila N. Muranova, Vyatcheslav V. Andrianov, Khalil L. Gainutdinov   +3 more
doaj   +1 more source

Better, worse, or different than expected: on the role of value and identity prediction errors in fear memory reactivation

Scientific Reports, 2022
Although reconsolidation-based interventions constitute a promising new avenue to treating fear and anxieties disorders, the success of the intervention is not guaranteed.
A. M. V. Gerlicher, S. A. Verweij, M. Kindt   +2 more
doaj   +1 more source

Enhancement of fear memory by retrieval through reconsolidation

eLife, 2014
Memory retrieval is considered to have roles in memory enhancement. Recently, memory reconsolidation was suggested to reinforce or integrate new information into reactivated memory.
Hotaka Fukushima, Yue Zhang, Georgia Archbold, Rie Ishikawa, Karim Nader, Satoshi Kida   +5 more
doaj   +1 more source

High trait anxiety: a challenge for disrupting fear memory reconsolidation. [PDF]

PLoS ONE, 2013
Disrupting reconsolidation may be promising in the treatment of anxiety disorders but the fear-reducing effects are thus far solely demonstrated in the average organism.
Marieke Soeter, Merel Kindt
doaj   +1 more source

Disrupting reconsolidation by PKA inhibitor in BLA reduces heroin-seeking behavior

Frontiers in Cellular Neuroscience, 2022
Drug abuse is considered a maladaptive pathology of emotional memory and is associated with craving and relapse induced by drug-associated stimuli or drugs.
Yanghui Zhang, Haoxian Li, Ting Hu, Ting Hu, Zijin Zhao, Zijin Zhao, Qing Liu, Qing Liu, Haoyu Li, Haoyu Li   +9 more
doaj   +1 more source

Reconsolidation and the Dynamic Nature of Memory [PDF]

Cold Spring Harbor Perspectives in Biology, 2015
Memory reconsolidation is the process in which reactivated long-term memory (LTM) becomes transiently sensitive to amnesic agents that are effective at consolidation. The phenomenon was first described more than 50 years ago but did not fit the dominant paradigm that posited that consolidation takes place only once per LTM item.
openaire   +2 more sources

Does the Loss of Autobiographical Memories Contribute to the Therapeutic Effect of Electroconvulsive Therapy?

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Objective For decades, a persistent claim has been that autobiographical memory loss after electroconvulsive therapy (ECT) for depression might actually contribute to ECT efficacy by reducing or even eliminating autobiographical memories. To test this claim, the primary aim of this study is to examine the association between autobiographical ...
Mike van Kessel, Joris van der Vlugt‐Molenaar, Isidoor O. Bergfeld, Eric van Exel, Jaap Murre, Jasmien Obbels, Pascal Sienaert, Kristof Vansteelandt, Esmée Verwijk   +8 more
wiley   +1 more source

Psychological change processes in alcohol use disorder: A qualitative study of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) with cognitive behavioural therapy

Addiction, EarlyView.
Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, James J. Rucker, Anthony Cleare, John Marsden   +6 more
wiley   +1 more source