Results 51 to 60 of about 1,728,317 (155)

The role of reconsolidation and the dynamic process of long-term memory formation and storage

Frontiers in Behavioral Neuroscience, 2011
It is becoming increasingly clear that the processes of memory formation and storage are exquisitely dynamic. Elucidating the nature and temporal evolution of the biological changes that accompany encoding, storage and retrieval is key to understand ...
Cristina M Alberini
doaj   +1 more source

DNA methyltransferase activity in the basolateral amygdala is critical for reconsolidation of a heroin reward memory

Frontiers in Molecular Neuroscience, 2022
The persistence of drug memory contributes to relapse to drug seeking. The association between repeated drug exposure and drug-related cues leads to cravings triggered by drug-paired cues.
Shuyi Qian, Cuijie Shi, Shihao Huang, Chang Yang, Yixiao Luo   +4 more
doaj   +1 more source

Altered prefrontal suppression of striatal activity during intrusive images in obsessive‐compulsive disorder

Psychiatry and Clinical Neurosciences, EarlyView.
Background Current models of obsessive‐compulsive disorder (OCD) emphasize dysfunction in frontostriatal circuits that support flexible behavioral control, leading to impulsive and compulsive actions. However, how these disruptions contribute to obsessions and intrusive thoughts remains poorly understood.
Anaïs Vandevelde, Sonia Dollfus, Pierre Gagnepain   +2 more
wiley   +1 more source

Targeting drug memory reconsolidation: a neural analysis. [PDF]

, 2020
Addiction can be conceptualised as a disorder of maladaptive learning and memory. Therefore, maladaptive drug memories supporting drug-seeking and relapse behaviours may present novel treatment targets for therapeutic approaches based upon ...
Cahill, Emma N, Taujanskaité, Ursule, Milton, Amy L.   +2 more
core   +2 more sources

Effects of Mineralocorticoid Receptors Blockade on FearMemory Reconsolidation in Rats

Basic and Clinical Neuroscience, 2011
Reconsolidation memory is defined as a process in which the retrieval of a previously consolidated memory returns to a labile state which is then subject to stabilization.
Ali Rashidy-Pour, Saeed Nikzad, Roghyeh Pakdel, Abbas Ali Vafaei   +3 more
doaj   +2 more sources

Efficacy and safety of ketamine for post‐traumatic stress disorder: A systematic review with narrative synthesis and consideration of military and veteran populations

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 4, December 2026.
Abstract Post‐traumatic stress disorder (PTSD) is a debilitating disorder with limited pharmaceutical treatment options. Ketamine, a noncompetitive N‐methyl‐d‐aspartate (NMDA) receptor antagonist with rapid‐onset effects, has emerged as a potential treatment, particularly for patients who do not respond to first‐line therapies.
Mary Ivasyutyn, Saajan Bhakta
wiley   +1 more source

Combining Cognitive Training and Brain Stimulation: A Novel Approach to Address Disordered Eating and Antipsychotic‐Induced Weight Gain in People With Severe Mental Illness

Early Intervention in Psychiatry, Volume 20, Issue 11, November 2026.
ABSTRACT Background Antipsychotic‐induced weight gain is a distressing side effect that most often occurs within the first 3–6 months of pharmacological initiation, significantly increasing cardiometabolic risk and mortality in individuals with severe mental illness.
Mariana Lopes, Dina Monssen, Luiza Grycuk, Gemma Gordon, Fiona Gaughran, Iain C. Campbell, Ulrike Schmidt   +6 more
wiley   +1 more source

Consolidation/reconsolidation therapies for the prevention and treatment of PTSD and re-experiencing: a systematic review and meta-analysis

Translational Psychiatry, 2021
Translational research highlights the potential of novel 'memory consolidation/reconsolidation therapies' to treat re-experiencing symptoms and post-traumatic stress disorder (PTSD).
Laurence Astill Wright, Louise Horstmann, Emily A. Holmes, Jonathan I. Bisson   +3 more
doaj   +1 more source

Does the Loss of Autobiographical Memories Contribute to the Therapeutic Effect of Electroconvulsive Therapy?

Acta Psychiatrica Scandinavica, Volume 154, Issue 4, Page 286-295, October 2026.
ABSTRACT Objective For decades, a persistent claim has been that autobiographical memory loss after electroconvulsive therapy (ECT) for depression might actually contribute to ECT efficacy by reducing or even eliminating autobiographical memories. To test this claim, the primary aim of this study is to examine the association between autobiographical ...
Mike van Kessel, Joris van der Vlugt‐Molenaar, Isidoor O. Bergfeld, Eric van Exel, Jaap Murre, Jasmien Obbels, Pascal Sienaert, Kristof Vansteelandt, Esmée Verwijk   +8 more
wiley   +1 more source

Chronic Pre‐Trauma Corticosterone Attenuates Trauma Memory Formation and Alters Gene Expression in Glucocorticoid Signalling Pathways

Genes, Brain and Behavior, Volume 25, Issue 5, October 2026.
The graphical abstract outlines the experimental workflow and key findings, showing how chronic or acute corticosterone elevations alter FC‐induced molecular and behavioural changes during trauma memory formation, consolidation, and recall. Abbreviations: Cort.—Corticosterone; FC—Fear Conditioning; PRPs—Plasticity‐Related Proteins.
Gia Kutelia, Zurab Kuchukashvili, Rusiko Ansiani, Roza Bukia, Manana Chikovani, Butsiko Chkhartishvili, Nanuli Doreulee   +6 more
wiley   +1 more source