Results 51 to 60 of about 454 (129)

DNA methyltransferase activity in the basolateral amygdala is critical for reconsolidation of a heroin reward memory

Frontiers in Molecular Neuroscience, 2022
The persistence of drug memory contributes to relapse to drug seeking. The association between repeated drug exposure and drug-related cues leads to cravings triggered by drug-paired cues.
Shuyi Qian, Cuijie Shi, Shihao Huang, Chang Yang, Yixiao Luo   +4 more
doaj   +1 more source

The neuropsychological impact of early childhood trauma on cognitive development: A narrative review of mechanisms, outcomes, and interventions

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
Abstract Research indicates that early traumatic experiences can profoundly affect a child's ability to manage emotions, develop social skills, and adapt effectively. Still, the impact of trauma on children goes beyond just emotional and behavioral dimensions.
Kalliopi Megari, Kremena Dinkova Genova
wiley   +1 more source

Substance‐related intrusive memories in cocaine use disorder are different from but associated with craving

Addiction, Volume 121, Issue 9, Page 2504-2517, September 2026.
Abstract Background and aims Cocaine use disorder (CUD) is a significant global health concern, characterized by persistent craving despite severe consequences. Recent theories highlight maladaptive memory processes – such as intrusive, vivid recollections of past substance use that arise spontaneously in daily life – as key contributors to craving and
Amelie Zacher, Lina Dietiker, Victoria Häffner, Francesco Bavato, Birgit Kleim, Boris B. Quednow   +5 more
wiley   +1 more source

Memory: Reconsolidation Allows Modification of Motor Memories [PDF]

Current Biology, 2010
A recent study using non-invasive transcranial magnetic stimulation has revealed how specific brain processing during memory reactivation makes possible the modification of existing memories that is required for motor learning.
openaire   +3 more sources

The Role of Meprins on the Brain Extracellular Matrix and Perineuronal Nets

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Meprin β overexpression is implicated in Alzheimer's Disease. Recent studies identified brevican as a meprin β substrate, and this study demonstrates that meprin α co‐expression enhances meprin β‐mediated brevican cleavage. Further, neurocan and RPTPζ were identified as novel meprin β substrates in an N‐terminomics analysis of meprin β transgenic mice,
Simon Kreiselmaier, Maximilian Keller, Leonardo Nardi, Constantin Mueller, Nele von Wiegen, Kira Bickenbach, Lea Gröbner, Mohammad Abukhalaf, Andreas Tholey, Margareta M. Mueller, Hagen Körschgen, Michael J. Schmeisser, Christoph Becker‐Pauly, Claus U. Pietrzik   +13 more
wiley   +1 more source

Exercise, Demethylase FTO, Neurological Disorders, and Neuropathic Pain: Potential Molecular Mechanisms

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
This review summarizes the role of FTO‐regulated m6A modification in Alzheimer's disease, Parkinson's disease, depression, and neuropathic pain. Exercise may ameliorate neural plasticity and neuronal excitability by downregulating FTO and enhancing m6A modification. We propose that FTO could serve as a potential epigenetic target through which exercise
Yanan Zheng, Yili Zheng, Peijie Chen, Xueqiang Wang   +3 more
wiley   +1 more source

Reconsolidation and extinction of an appetitive pavlovian memory [PDF]

Neurobiology of Learning and Memory, 2013
When memories are retrieved, they can enter a labile state during which the memory may be modified and subsequently restabilized through the process of reconsolidation. However, this does not occur in all situations, and certain "boundary conditions" determine whether a memory will undergo reconsolidation. Naïve male lister hooded rats were trained for
Flavell, Charlotte R., Lee, Jonathan L. C.   +1 more
openaire   +4 more sources

Consolidation/reconsolidation therapies for the prevention and treatment of PTSD and re-experiencing: a systematic review and meta-analysis

Translational Psychiatry, 2021
Translational research highlights the potential of novel 'memory consolidation/reconsolidation therapies' to treat re-experiencing symptoms and post-traumatic stress disorder (PTSD).
Laurence Astill Wright, Louise Horstmann, Emily A. Holmes, Jonathan I. Bisson   +3 more
doaj   +1 more source

Cannabidiol in Anorexia Nervosa: A Double‐Blind Randomized Placebo Controlled Pilot Study to Test Safety, Pharmacokinetics, and Symptom Change

International Journal of Eating Disorders, Volume 59, Issue 7, Page 1576-1587, July 2026.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder marked by an intense fear of gaining weight and persistent body dissatisfaction, both during periods of underweight and after weight restoration. The endocannabinoid system may offer therapeutic benefits, particularly in reducing anxiety.
Neha Sahota, David J. Grelotti, Tyler Nguyen, Walter H. Kaye, Skylar Swindle, Raymond Suhandynata, Spencer Seely, Megan E. Shott, Guido K. W. Frank   +8 more
wiley   +1 more source

Massage Regulates Brain Plasticity in Chronic Sciatic Nerve Compression Injury Rats: A Study Based on Resting‐State Functional Magnetic Resonance Imaging

Brain and Behavior, Volume 16, Issue 6, June 2026.
Resting‐state functional magnetic resonance imaging analysis of chronic constriction injury rats after massage therapy. ABSTRACT Background Neuropathic pain (NP) is associated with maladaptive functional reorganization of the brain, yet the central mechanisms through which massage therapy exerts its analgesic effects remain poorly understood.
Lanting Huang, Xuekun Zhou, Lechun Chen, Chenyu Wang, Hao Wang, Huanzhen Zhang, Changzheng Jiang, Shuijin Chen, Jingjing Jiang, Qiangwen Xie, Zhigang Lin   +10 more
wiley   +1 more source