Reconsolidation and psychopathology: Moving towards reconsolidation-based treatments [PDF]
Neurobiology of Learning and Memory, 2017 Interfering with memory reconsolidation has valuable potential to be used as a treatment for maladaptive memories and psychiatric disorders. Numerous studies suggest that reconsolidation-based therapies may benefit psychiatric populations, but much remains unanswered.
Amber B, Dunbar, Jane R, Taylor
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Recall and reconsolidation of contextual fear memory: differential control by ERK and Zif268 expression dosage. [PDF]
PLoS ONE, 2013 Compelling evidence points to the existence of independent cellular processes involved in the consolidation and reconsolidation of memory. For instance, a double dissociation has been reported between hippocampal Extracellular-Regulated Kinase-1/2 (ERK1 ...
Antoine Besnard +2 more
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Reconsolidation of episodic memories:a subtle reminder triggers integration of new information [PDF]
, 2007 Recent demonstrations of "reconsolidation" suggest that memories can be modified when they are reactivated. Reconsolidation has been observed in human procedural memory and in implicit memory in infants.
Hardt, Oliver +3 more
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Focus on emotion as a catalyst of memory updating during reconsolidation [PDF]
, 2015 We share the idea of Lane et al. that successful psychotherapy exerts its effects through memory reconsolidation. To support it, we add further evidence that a behavioral interference may trigger memory update during reconsolidation.
Rohde, Kristina Barbara +5 more
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The role and dynamic of strengthening in the reconsolidation process in a human declarative memory: what decides the fate of recent and older memories? [PDF]
PLoS ONE, 2013 Several reports have shown that after specific reminders are presented, consolidated memories pass from a stable state to one in which the memory is reactivated. This reactivation implies that memories are labile and susceptible to amnesic agents.
Cecilia Forcato +2 more
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Drug memory reconsolidation: from molecular mechanisms to the clinical context
Translational Psychiatry, 2023 Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been proposed to be a therapeutic target for reducing the impact of emotional memories that can go awry in mental health disorders such as drug addiction (substance ...
Amy L. Milton
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Reconsolidation: A paradigm shift
Brain Research Bulletin, 2022 This commentary is part of a special issue honoring Karim Nader and his focal role in igniting the reconsolidation field. The commentary describes in broad strokes the evolution of the field, its branches, major challenges, and future endeavors.
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Disrupting reconsolidation by PKA inhibitor in BLA reduces heroin-seeking behavior
Frontiers in Cellular Neuroscience, 2022 Drug abuse is considered a maladaptive pathology of emotional memory and is associated with craving and relapse induced by drug-associated stimuli or drugs.
Yanghui Zhang +9 more
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Reconsolidation of drug memories [PDF]
Neuroscience & Biobehavioral Reviews, 2012 Persistent, unwanted memories are believed to be key contributors to drug addiction and the chronic relapse problem over the lifetime of the addict. Contrary to the long-held idea that memories are static and fixed, new studies in the last decade have shown that memories are dynamic and changeable.
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, 2023 Reconsolidation results in the restabilisation, and thus persistence, of a memory made labile by retrieval, and interfering with this process is thought to enable modification or weakening of the original trace. As such, reconsolidation-blockade has been
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