Results 31 to 40 of about 8,650 (204)

Rescue of long-term memory after reconsolidation blockade [PDF]

open access: yes, 2015
Memory reconsolidation is considered to be the process whereby stored memories become labile on recall, allowing updating. Blocking the restabilization of a memory during reconsolidation is held to result in a permanent amnesia. The targeted knockdown of
Hall, Jeremy   +3 more
core   +1 more source

Consolidation, reconsolidation, and extinction of contextual fear memory depend on de novo protein synthesis in the locus coeruleus

open access: yesBrain Research Bulletin, 2023
Memory consolidation is the process underlying the stabilization of labile short-term memory and the generation of long-term memory for persistent memory storage. The retrieval of contextual fear memory induces two distinct and opposite memory processes:
Yu Arihara, Yudai Fukuyama, Satoshi Kida
doaj   +1 more source

Acid-sensing ion channel 1a regulates the specificity of reconsolidation of conditioned threat responses

open access: yesJCI Insight, 2022
Recent research on altering threat memory has focused on a reconsolidation window. During reconsolidation, threat memories are retrieved and become labile.
Erin E. Koffman   +10 more
doaj   +1 more source

Consolidation/reconsolidation therapies for the prevention and treatment of PTSD and re-experiencing: a systematic review and meta-analysis

open access: yesTranslational Psychiatry, 2021
Translational research highlights the potential of novel 'memory consolidation/reconsolidation therapies' to treat re-experiencing symptoms and post-traumatic stress disorder (PTSD).
Laurence Astill Wright   +3 more
doaj   +1 more source

Focus on emotion as a catalyst of memory updating during reconsolidation [PDF]

open access: yes, 2015
We share the idea of Lane et al. that successful psychotherapy exerts its effects through memory reconsolidation. To support it, we add further evidence that a behavioral interference may trigger memory update during reconsolidation.
Rohde, Kristina Barbara   +2 more
core   +2 more sources

The role and dynamic of strengthening in the reconsolidation process in a human declarative memory: what decides the fate of recent and older memories? [PDF]

open access: yesPLoS ONE, 2013
Several reports have shown that after specific reminders are presented, consolidated memories pass from a stable state to one in which the memory is reactivated. This reactivation implies that memories are labile and susceptible to amnesic agents.
Cecilia Forcato   +2 more
doaj   +1 more source

Drug memory reconsolidation: from molecular mechanisms to the clinical context

open access: yesTranslational Psychiatry, 2023
Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been proposed to be a therapeutic target for reducing the impact of emotional memories that can go awry in mental health disorders such as drug addiction (substance ...
Amy L. Milton
doaj   +1 more source

Disrupting reconsolidation by PKA inhibitor in BLA reduces heroin-seeking behavior

open access: yesFrontiers in Cellular Neuroscience, 2022
Drug abuse is considered a maladaptive pathology of emotional memory and is associated with craving and relapse induced by drug-associated stimuli or drugs.
Yanghui Zhang   +9 more
doaj   +1 more source

Reconsolidation: A paradigm shift

open access: yesBrain Research Bulletin, 2022
This commentary is part of a special issue honoring Karim Nader and his focal role in igniting the reconsolidation field. The commentary describes in broad strokes the evolution of the field, its branches, major challenges, and future endeavors.
openaire   +2 more sources

Reconsolidation of drug memories [PDF]

open access: yesNeuroscience & Biobehavioral Reviews, 2012
Persistent, unwanted memories are believed to be key contributors to drug addiction and the chronic relapse problem over the lifetime of the addict. Contrary to the long-held idea that memories are static and fixed, new studies in the last decade have shown that memories are dynamic and changeable.
openaire   +2 more sources

Home - About - Disclaimer - Privacy