Results 51 to 60 of about 8,650 (204)

High trait anxiety: a challenge for disrupting fear memory reconsolidation. [PDF]

PLoS ONE, 2013
Disrupting reconsolidation may be promising in the treatment of anxiety disorders but the fear-reducing effects are thus far solely demonstrated in the average organism.
Marieke Soeter, Merel Kindt
doaj   +1 more source

Psychological change processes in alcohol use disorder: A qualitative study of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) with cognitive behavioural therapy

Addiction, EarlyView.
Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, James J. Rucker, Anthony Cleare, John Marsden   +6 more
wiley   +1 more source

Envolvimento da síntese proteica no hipocampo dorsal na tolerância ao efeito ansiolítico do midazolam observada na terceira exposição ao labirinto em cruz elevado em ratos [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013Em roedores, a experiência prévia ao labirinto em cruz elevado (LCE) compromete, em uma re ...

core  

Imagery rescripting for generalized anxiety disorder: A case series

British Journal of Clinical Psychology, EarlyView.
Abstract Introduction This is the first clinical pilot to explore the feasibility, acceptability and preliminary efficacy of imagery rescripting in individuals with a diagnosis of generalized anxiety disorder (GAD). Methods Participants with GAD (N = 18) attended assessment and 10 weekly sessions of imagery rescripting with a psychologist in person or ...
L. Stavropoulos, A. B. Phipps, I. Sabel, D. D. J. Cooper, N. Briggs, J. M. Newby, J. R. Grisham   +6 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Revisitando os mecanismos de modulação noradrenérgica sobre as memórias de medo: do fisiológico ao disfuncional [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2015.O sistema noradrenérgico é implicado tradicionalmente no processamento das memórias emocionais por meio
Gazarini, Lucas
core  

Resilience and Vulnerability to Trauma: Early Life Interventions Modulate Aversive Memory Reconsolidation in the Dorsal Hippocampus

Frontiers in Molecular Neuroscience, 2019
Early life experiences program lifelong responses to stress. In agreement, resilience and vulnerability to psychopathologies, such as posttraumatic stress disorder (PTSD), have been suggested to depend on the early background. New therapies have targeted
Natividade de Sá Couto-Pereira, Natividade de Sá Couto-Pereira, Natividade de Sá Couto-Pereira, Carine Lampert, Aline dos Santos Vieira, Camilla Lazzaretti, Grasielle Clotildes Kincheski, Pablo Javier Espejo, Victor Alejandro Molina, Jorge Alberto Quillfeldt, Jorge Alberto Quillfeldt, Carla Dalmaz, Carla Dalmaz, Carla Dalmaz   +13 more
doaj   +1 more source

Avoidance memory requires CaMKII activity to persist after recall

Molecular Brain, 2021
Avoidance memory is destabilized when recalled concurrently with conflicting information, and must undergo a hippocampus-dependent restabilization process called reconsolidation to persist. CaMKII is a serine/threonine protein kinase essential for memory
Andressa Radiske, Maria Carolina Gonzalez, Janine I. Rossato, Gênedy Apolinário, João R. de Oliveira, Lia R. M. Bevilaqua, Martín Cammarota   +6 more
doaj   +1 more source

Extracellular signal-regulated kinase in the basolateral amygdala is required for reconsolidation of heroin-associated memory

Frontiers in Molecular Neuroscience, 2022
Reconsolidation of heroin-associated memory is an independent memory process that occurs following retrieval, which is essential for the sustained capacity of an associative drug stimulus to precipitate heroin-seeking.
Haoyu Li, Haoyu Li, Haoyu Li, Ting Hu, Ting Hu, Ting Hu, Yanghui Zhang, Zijin Zhao, Zijin Zhao, Zijin Zhao, Qing Liu, Qing Liu, Qing Liu, Zihua Chen, Zihua Chen, Si Chen, Si Chen, Si Chen   +17 more
doaj   +1 more source

Restorative Journeys: Youth Offending Trajectories and Victim Recovery Following Restorative Justice Conferencing

The Howard Journal of Crime and Justice, EarlyView.
ABSTRACT Restorative justice (RJ) is associated with offenders’ movement away from crime and victim recovery. However, little is known about the circumstances under which RJ can simultaneously achieve the dual objectives. Using secondary data from the South Australian Juvenile Justice study, this research examines how RJ conferencing shapes short‐term ...
Masahiro Suzuki
wiley   +1 more source