Results 51 to 60 of about 8,759 (205)

DNA methyltransferase activity in the basolateral amygdala is critical for reconsolidation of a heroin reward memory

Frontiers in Molecular Neuroscience, 2022
The persistence of drug memory contributes to relapse to drug seeking. The association between repeated drug exposure and drug-related cues leads to cravings triggered by drug-paired cues.
Shuyi Qian, Cuijie Shi, Shihao Huang, Chang Yang, Yixiao Luo   +4 more
doaj   +1 more source

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee, Gayeon Kim, Ellison R. Black, Seonil Kim   +3 more
wiley   +1 more source

High trait anxiety: a challenge for disrupting fear memory reconsolidation. [PDF]

PLoS ONE, 2013
Disrupting reconsolidation may be promising in the treatment of anxiety disorders but the fear-reducing effects are thus far solely demonstrated in the average organism.
Marieke Soeter, Merel Kindt
doaj   +1 more source

Enhancing cognition by affecting memory reconsolidation [PDF]

, 2015
Fully consolidated associative memories can undergo a retrieval-dependent reconsolidation process, which allows for the updating and strengthening of the original association.
Amy L Milton (16272185), Barry J Everitt (16272188), Emiliano Merlo (5941004)   +2 more
core   +3 more sources

Effect of Ammonium Polyphosphate/Silicate Content on the Postfire Mechanics of Epoxy Glass‐Fiber Composites Using Facile Chocolate Bar‐Inspired Structures

Fire and Materials, Volume 49, Issue 3, Page 329-346, April 2025.
ABSTRACT This study investigates the postfire mechanical properties of epoxy glass‐fiber reinforced composites (EP GFRCs) using increasing concentrations of ammonium polyphosphate (APP) and inorganic silicate (InSi) to modify the char and fire residue.
Sruthi Sunder, Maria Jauregui Rozo, Sneha Inasu, Dietmar Meinel, Bernhard Schartel, Holger Ruckdäschel   +5 more
wiley   +1 more source

Improving Soil Health and Crop Yields Through Conservation Agriculture and Nutrient Management in Central India

Land Degradation &Development, EarlyView.
ABSTRACT Maintaining soil health and crop productivity in the semi‐arid Vertisols of central India poses a significant challenge under intensive agricultural practices. This 6‐year field study assessed the combined impact of different tillage methods, maize‐based crop rotations, and nitrogen management on soil's physical, chemical, and biological ...
Nishant K. Sinha, M. Mohanty, Somasundaram Jayaraman, Anuj Kumar Dwivedi, Deepak Singh, K. Sammi Reddy, M. Prabhakar, V. K. Singh, C. S. P. Ojha, V. P. Singh, Rituraj Shukla   +10 more
wiley   +1 more source

Resilience and Vulnerability to Trauma: Early Life Interventions Modulate Aversive Memory Reconsolidation in the Dorsal Hippocampus

Frontiers in Molecular Neuroscience, 2019
Early life experiences program lifelong responses to stress. In agreement, resilience and vulnerability to psychopathologies, such as posttraumatic stress disorder (PTSD), have been suggested to depend on the early background. New therapies have targeted
Natividade de Sá Couto-Pereira, Natividade de Sá Couto-Pereira, Natividade de Sá Couto-Pereira, Carine Lampert, Aline dos Santos Vieira, Camilla Lazzaretti, Grasielle Clotildes Kincheski, Pablo Javier Espejo, Victor Alejandro Molina, Jorge Alberto Quillfeldt, Jorge Alberto Quillfeldt, Carla Dalmaz, Carla Dalmaz, Carla Dalmaz   +13 more
doaj   +1 more source

Avoidance memory requires CaMKII activity to persist after recall

Molecular Brain, 2021
Avoidance memory is destabilized when recalled concurrently with conflicting information, and must undergo a hippocampus-dependent restabilization process called reconsolidation to persist. CaMKII is a serine/threonine protein kinase essential for memory
Andressa Radiske, Maria Carolina Gonzalez, Janine I. Rossato, Gênedy Apolinário, João R. de Oliveira, Lia R. M. Bevilaqua, Martín Cammarota   +6 more
doaj   +1 more source

Extracellular signal-regulated kinase in the basolateral amygdala is required for reconsolidation of heroin-associated memory

Frontiers in Molecular Neuroscience, 2022
Reconsolidation of heroin-associated memory is an independent memory process that occurs following retrieval, which is essential for the sustained capacity of an associative drug stimulus to precipitate heroin-seeking.
Haoyu Li, Haoyu Li, Haoyu Li, Ting Hu, Ting Hu, Ting Hu, Yanghui Zhang, Zijin Zhao, Zijin Zhao, Zijin Zhao, Qing Liu, Qing Liu, Qing Liu, Zihua Chen, Zihua Chen, Si Chen, Si Chen, Si Chen   +17 more
doaj   +1 more source

Psychological change processes in alcohol use disorder: A qualitative study of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) with cognitive behavioural therapy

Addiction, EarlyView.
Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, James J. Rucker, Anthony Cleare, John Marsden   +6 more
wiley   +1 more source