Results 41 to 50 of about 8,759 (205)

Retrieval cues that trigger reconsolidation of associative fear memory are not necessarily an exact replica of the original learning experience

Frontiers in Behavioral Neuroscience, 2015
Disrupting the process of memory reconsolidation may point to a novel therapeutic strategy for the permanent reduction of fear in patients suffering from anxiety disorders.
Marieke eSoeter, Merel eKindt
doaj   +1 more source

Reconsolidation of a well-learned instrumental memory [PDF]

, 2014
Once consolidated, memories are dynamic entities that go through phases of instability in order to be updated with new information, via a process of reconsolidation.
Exton-McGuinness, Marc T J, Lee, Jonathan L C; id_orcid, Patton, Rosemary C, Sacco, Lawrence B   +3 more
core   +1 more source

Experimental Study of Dynamic Characteristics of Tailings With Different Reconsolidation Degrees After Liquefaction

Frontiers in Earth Science, 2022
The construction period of most tailing ponds generally lasts for more than 10 years or even decades. During this period, it may be affected by more than one earthquake and is often subjected to vibrations generated by mining activities.
Wensong Wang, Wensong Wang, Guansen Cao, Guansen Cao, Ye Li, Yuxi Zhou, Ting Lu, Ya Wang, Binbin Zheng   +8 more
doaj   +1 more source

Inhibition of Glycogen Synthase Kinase 3β Activity in the Basolateral Amygdala Disrupts Reconsolidation and Attenuates Heroin Relapse

Frontiers in Molecular Neuroscience, 2022
Exposure to a heroin-associated conditioned stimulus can reactivate drug reward memory, trigger drug cravings, and induce relapse in heroin addicts. The amygdala, a brain region related to emotions and motivation, is involved in processing rewarding ...
Yuanyang Xie, Yuanyang Xie, Yingfan Zhang, Ting Hu, Ting Hu, Zijin Zhao, Zijin Zhao, Qing Liu, Qing Liu, Haoyu Li, Haoyu Li   +10 more
doaj   +1 more source

Modeling reconsolidation in kernel associative memory. [PDF]

PLoS ONE, 2013
Memory reconsolidation is a central process enabling adaptive memory and the perception of a constantly changing reality. It causes memories to be strengthened, weakened or changed following their recall.
Dimitri Nowicki, Patrick Verga, Hava Siegelmann   +2 more
doaj   +1 more source

5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex

eLife, 2018
Context-dependent memories may guide adaptive behavior relaying in previous experience while updating stored information through reconsolidation. Retrieval can be triggered by partial and shared cues.
Juan Facundo Morici, Magdalena Miranda, Francisco Tomás Gallo, Belén Zanoni, Pedro Bekinschtein, Noelia V Weisstaub   +5 more
doaj   +1 more source

Pharmacological interventions during the process of reconsolidation of aversive memories: A systematic review

Neurobiology of Stress, 2019
Reconsolidation is the return of a memory to a transient state of lability, following memory consolidation, that can occur when memories are evoked.
Lívia Maria Bolsoni, Antonio Waldo Zuardi   +1 more
doaj   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

Advanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao, Yu‐Xin Zhang, Xiao‐Xing Liu, Zi‐Hang Li, Tang‐Sheng Lu, Jia‐Hui Deng, Wen Zhang, Peng Li, Xiao Lin, Shu‐Fei Feng, Ting‐Ting Li, Shi‐Qiu Meng, Xiang‐Dong Tang, Tian‐Ye Jia, Trevor W. Robbins, Jie Shi, Ying Han, Yan‐Xue Xue, Lin Lu, Kai Yuan   +19 more
wiley   +1 more source

Efeito do canabidiol sobre a reconsolidação da memória de medo ao contexto: envolvimento dos receptores CB1 do córtex pré-límbico [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.A busca por drogas que prejudicam a reconsolidação de memórias traumáticas pode ter um impacto ...
Stern, Cristina Aparecida Jark
core