Results 81 to 90 of about 1,279,508 (285)

Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths

Annals of Neurology, EarlyView.
Objective Though it is widely known that tau deposition affects brain structure, the precise localization of these effects is poorly understood, especially in relation to gyral and sulcal anatomy. We investigated whether tau pathology in Alzheimer's disease (AD) preferentially affects sulci, and particularly sulcal depths.
Samira A. Maboudian, Corrina S. Fonseca, Adam C. Martersteck, Yishu Chao, Yuheng Chen, Daniela Ushizima, Duygu Tosun, Lea T. Grinberg, Kevin S. Weiner, William J. Jagust, for the Alzheimer's Disease Neuroimaging Initiative   +10 more
wiley   +1 more source

Amygdala Nuclei Volumes Are Selectively Associated With Social Network Size in Homeless and Precariously Housed Persons

Frontiers in Behavioral Neuroscience, 2020
Objective: The amygdala is a brain region comprised of a group of functionally distinct nuclei that play a central role in social behavior. In homeless and precariously housed individuals, high rates of multimorbidity, and structural aspects of the ...
Paul W. Jones, Allen E. Thornton, Andrea A. Jones, Verena M. Knerich, Donna J. Lang, Melissa L. Woodward, William J. Panenka, Wayne Su, Alasdair M. Barr, Tari Buchanan, William G. Honer, Kristina M. Gicas, Kristina M. Gicas   +12 more
doaj   +1 more source

Fear conditioning enhances short-latency auditory responses of lateral amygdala neurons: parallel recordings in the freely behaving rat.

Neuron, 1995
The lateral nucleus of the amygdala (LA) is the first site in the amygdala where the plasticity underlying fear conditioning could occur. We simultaneously recorded from multiple LA neurons in freely moving rats during fear conditioning trials in which ...
G. Quirk, J. Repa, Joseph E LeDoux
semanticscholar   +1 more source

Changes in Intrinsic Activity of the Primary Somatosensory Cortex Causally Explain Differences in Emotion Perception in Autism

Autism Research, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is characterized by certain difficulties in emotion‐related processing. Recent research using electroencephalography (EEG) to measure somatosensory evoked potentials during emotion perception has shown reduced embodiment of emotional expressions in autistic compared to neurotypical individuals, independently from
Martina Fanghella, Danai Dima, Dimitrios Pinotsis, Sebastian B. Gaigg, Beatriz Calvo‐Merino, Bettina Forster   +5 more
wiley   +1 more source

Altered Brain Structure in an ATRX‐Deficient Mouse Model of Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Mutations in the ATRX gene are a primary cause of alpha‐thalassemia intellectual disability X‐linked (ATRX) syndrome, which is characterized by intellectual disability, autism, and a range of brain structural abnormalities, including microcephaly.
Katherine Quesnel, Jacob Ellegood, Jason P. Lerch, Nathalie G. Bérubé   +3 more
wiley   +1 more source

Orexin modulates behavioral fear expression through the locus coeruleus

Nature Communications, 2017
Vigilance involves the activation of orexinergic neurons in the lateral hypothalamus (LH-ox). Here the authors report the functional role of a monosynaptically connected circuit with orexinergic neurons connected to noradrenergic neurons in the locus ...
Shingo Soya, Tohru M. Takahashi, Thomas J. McHugh, Takashi Maejima, Stefan Herlitze, Manabu Abe, Kenji Sakimura, Takeshi Sakurai   +7 more
doaj   +1 more source

The Role of Actin Cytoskeleton in Memory Formation in Amygdala

Frontiers in Molecular Neuroscience, 2016
The central, lateral and basolateral amygdala nuclei are essential for the formation of long-term memories including emotional and drug-related memories. The study of cellular and molecular mechanisms underpinning memory in amygdala may shed light on the
Raphael eLamprecht
doaj   +1 more source

CREB regulates spine density of lateral amygdala neurons: implications for memory allocation

Frontiers in Behavioral Neuroscience, 2013
Neurons may compete against one another for integration into a memory trace. Specifically, neurons in the lateral nucleus of the amygdala with relatively higher levels of cAMP Responsive Element Binding Protein (CREB) seem to be preferentially allocated ...
D. Sargin, Valentina Mercaldo, A. Yiu, Gemma V. Higgs, Jin-Hee Han, P. Frankland, S. Josselyn   +6 more
semanticscholar   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, EarlyView.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source

Mechanisms contributing to the induction and storage of Pavlovian fear memories in the lateral amygdala

Learning & memory (Cold Spring Harbor, N.Y.), 2013
The relative contributions of plasticity in the amygdala vs. its afferent pathways to conditioned fear remain controversial. Some believe that thalamic and cortical neurons transmitting information about the conditioned stimulus (CS) to the lateral ...
Dongbeom Kim, D. Paré, S. Nair
semanticscholar   +1 more source