Results 21 to 30 of about 37,718 (264)

Numerical Simulation Study on the Bearing Characteristics of Rectangular Pile Foundations Under Combined Loading in Slope Topography

open access: yesBuildings
Rectangular piles are increasingly utilized in engineering due to their high lateral bearing capacity, which benefits from an adjustable cross-sectional stiffness.
Tao Chen   +7 more
doaj   +1 more source

Effect of Solidified Depth on the Vertical Compressive Bearing Characteristics of the Soil Continuously Solidified Pile Group Foundation

open access: yesApplied Sciences, 2023
To meet the ultra-high bearing capacity design requirements of pile foundations under geological conditions without a good holding layer, we invented a new type of group pile foundation with the soil continuously solidified between piles (hereinafter ...
Tao Sun   +6 more
doaj   +1 more source

Triple-Shear Unified Solution for Bearing Capacity of Unsaturated Soft Soil Foundations with Hard Crust

open access: yesGeofluids, 2022
The bearing capacity of unsaturated soft soil foundations is affected by natural or artificial hard crust, due to the stress diffusion and closure effect.
Xueye Cao   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Simulation analysis of energy absorption characteristics of hyperbolic shallow shell anti-impact energy absorbing components

open access: yesMeikuang Anquan
To enhance the impact resistance and energy absorption performance of hydraulic supports in mitigating coal mine rock burst, a hyperbolic shallow shell anti-impact energy-absorbing component was designed.
Dong AN   +4 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Experimental study on bearing mechanism of screw cast-in-place piles under vertical loads

open access: yesYantu gongcheng xuebao, 2021
The screw cast-in-place pile is a kind of variable-section cast-in-place pile with cylindrical top and threaded bottom. Due to its special construction technology and section form, the bearing mechanism of screw piles is different from that of piles with
WANG Shu-guang 1, 2, FENG Zhe 3, TANG Jian-zhong 1, ZHAO Zhi-peng 1
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

A Study on the Lateral Load Capacity of a Novel Hybrid Monopile via a Centrifuge Model Test

open access: yesEnergies, 2023
Large-diameter monopiles that can safely support the lateral loads caused by wind and waves have been widely used for the foundations of offshore wind turbines. However, when the penetration depth is insufficient as a result of the presence of thick soft
Ju-Hyung Lee   +4 more
doaj   +1 more source

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