Results 31 to 40 of about 37,718 (264)

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Performance of Round-Ended Concrete-Filled Steel Tubular Columns Under Combined Compression–Bending–Shear Loading

Buildings
This study develops and validates a finite element model for round-ended concrete-filled steel tubular (CFST) columns subjected to combined compression–bending–shear loading using ABAQUS.
Yan Peng, Junfeng Liu, Junping He, Zongfeng He, Fan Deng   +4 more
doaj   +1 more source

Bearing Mechanical Characteristics and Stability Analysis of Deep-water Suction Pile

Shiyou jixie, 2023
The suction pile is characterized by high bearing capacity and a simple construction process and has broad application prospects in deep-water drilling exploration and well construction.The load-bearing characteristics of suction piles under different ...
Xu Dongsheng, Yang Jin, Fan Jianchun, Li Yanjun, Song Yu, Yan De   +5 more
doaj  

Vertical and Lateral Bearing Capacity of FRP Composite Sheet Piles in Soft Soil

Advances in Civil Engineering, 2020
Fiber-reinforced polymer (FRP) composite sheet piles are usually favored for slope and river-retaining structures due to their construction and environmental efficiency.
Zhe Wang, Shuwei Wu, Kaiwen Weng, Wangjing Yao, Sifa Xu, Zhouxiang Ding   +5 more
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Study on the Bearing Capacity of High-Cap Inclined Pile Foundations

Advances in Civil Engineering, 2022
To analyze the bearing capacity of high-cap inclined pile foundations based on foundation design in practical engineering, finite element models of single cap foundations and multi-cap foundations are established.
Guodong Shao, Juan Liu, Tonglei Wang, Yuping Liu   +3 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley   +1 more source

Study on the Lateral Performance of Large-Scale Steel Casing-Reinforced Concrete Pile Composite Members

Buildings
In order to investigate the lateral working performance of large-scale steel casing-reinforced concrete pile composite members, this paper sets up large-scale steel casing-reinforced concrete pile composite members with different slenderness ratios λ ...
Duoyin Wang, Wei Liu, Chenxi Qin, Mingjie Jiang, Baojiang Gao   +4 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source