Rapid and simultaneous detection of Campylobacter spp. and Salmonella spp. in chicken samples by duplex loop-mediated isothermal amplification coupled with a lateral flow biosensor assay. [PDF]
Sridapan T +5 more
europepmc +1 more source
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo +7 more
wiley +1 more source
Point of Care Testing and Recombinase Polymerase Amplification
Journal of Clinical Laboratory Analysis, EarlyView.
Manfred Weidmann, Ahmed Abd El Wahed
wiley +1 more source
Electrolyte‐gated nanoscale silicon field‐effect transistor sensors provide exceptional charge sensitivity and direct electrical readout. However, their sensing accuracy is fundamentally limited by low‐frequency noise and baseline drift. This review examines the origins of noise and drift in these sensors, summarizes the key mitigation strategies, and ...
Yingtao Yu +5 more
wiley +1 more source
Ultra-rapid and sensitive detection of African swine fever virus using multiple cross displacement amplification combined with nanoparticle-based lateral flow biosensor. [PDF]
Mao S +7 more
europepmc +1 more source
Multiple Single-Nucleotide Polymorphism Detection for Antimalarial Pyrimethamine Resistance via Allele-Specific PCR Coupled with Gold Nanoparticle-Based Lateral Flow Biosensor. [PDF]
Jiang T +9 more
europepmc +1 more source
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song +14 more
wiley +1 more source
A specific and ultrasensitive Cas12a/crRNA assay with recombinase polymerase amplification and lateral flow biosensor technology for the rapid detection of <i>Streptococcus pyogenes</i>. [PDF]
Cheng Y +7 more
europepmc +1 more source
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu +11 more
wiley +1 more source
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley +1 more source

