Results 171 to 180 of about 3,828,364 (261)

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

open access: yesSmall Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo   +7 more
wiley   +1 more source

Point of Care Testing and Recombinase Polymerase Amplification

open access: yes
Journal of Clinical Laboratory Analysis, EarlyView.
Manfred Weidmann, Ahmed Abd El Wahed
wiley   +1 more source

Low‐Frequency Noise and Stability in Electrolyte‐Gated Nanoscale Silicon Field‐Effect Transistor Sensors

open access: yesSmall Methods, EarlyView.
Electrolyte‐gated nanoscale silicon field‐effect transistor sensors provide exceptional charge sensitivity and direct electrical readout. However, their sensing accuracy is fundamentally limited by low‐frequency noise and baseline drift. This review examines the origins of noise and drift in these sensors, summarizes the key mitigation strategies, and ...
Yingtao Yu   +5 more
wiley   +1 more source

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

open access: yesVIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song   +14 more
wiley   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

open access: yesVIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu   +11 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

open access: yesVIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

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