Results 181 to 190 of about 8,142 (219)
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Analytical Biochemistry, 2021
MicroRNAs (miRNAs) are short RNA sequences found in eukaryotic cells and they are involved in several diseases pathogenesis including different types of cancers, metabolic and cardiovascular disorders. Thus, miRNAs circulating in serum, plasma, and other body fluids are employed as biomarkers for diagnostic and prognostic purposes and in assessment of ...
Niloofar, Khandan-Nasab +5 more
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MicroRNAs (miRNAs) are short RNA sequences found in eukaryotic cells and they are involved in several diseases pathogenesis including different types of cancers, metabolic and cardiovascular disorders. Thus, miRNAs circulating in serum, plasma, and other body fluids are employed as biomarkers for diagnostic and prognostic purposes and in assessment of ...
Niloofar, Khandan-Nasab +5 more
openaire +2 more sources
Gold nanorods-based lateral flow biosensors for sensitive detection of nucleic acids
Microchimica Acta, 2021A gold nanorod (AuNR)-based lateral flow nucleic acid biosensor (LFNAB) is reported for visual detection of DNA with a short test time and high sensitivity. AuNRs with an approximate length of 60 nm were utilized as a colored tag to label the detection DNA probe (Det-DNA).
Qingcai Yu +6 more
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Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2020
Vaspin is a protein present in human serum that can cause type-2 diabetes, obesity, and other cardiovascular diseases. We report fluorescent upconverting nanoparticles (UCNPs)-based lateral flow biosensor for ultrasensitive detection of Vaspin. A pair (primary and secondary) of cognate aptamers was used that has duo binding with Vaspin.
Muhammad Asad Ullah Khalid +2 more
exaly +3 more sources
Vaspin is a protein present in human serum that can cause type-2 diabetes, obesity, and other cardiovascular diseases. We report fluorescent upconverting nanoparticles (UCNPs)-based lateral flow biosensor for ultrasensitive detection of Vaspin. A pair (primary and secondary) of cognate aptamers was used that has duo binding with Vaspin.
Muhammad Asad Ullah Khalid +2 more
exaly +3 more sources
2016
A typical lateral flow biosensor employs a sandwich detection system and uses tracer(s) to generate detectable signal(s) (Figure 13.1). However, recent advances in nanomaterials offer a wide variety of improvement options, including new detection methodologies, signal transformation and improvements in sensitivity and specificity [4-6]. In this chapter,
Li, Jia, Macdonald, J
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A typical lateral flow biosensor employs a sandwich detection system and uses tracer(s) to generate detectable signal(s) (Figure 13.1). However, recent advances in nanomaterials offer a wide variety of improvement options, including new detection methodologies, signal transformation and improvements in sensitivity and specificity [4-6]. In this chapter,
Li, Jia, Macdonald, J
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An enzyme-amplified lateral flow strip biosensor for visual detection of MicroRNA-224
Talanta, 2016An enzyme-based dual-labeled nanoprobe is designed to fabricate a sensitive enzyme-amplified lateral flow biosensor for visual detection of mircoRNA-224 (miRNA-224). The recognition DNA probe (detection probe) and signal amplification enzyme (Horseradish peroxidase, HRP) are immobilized on gold nanoparticle (GNPs) surface, simultaneously.
Xueji Zhang, Xinlei Ma, Yongqiang Wen
exaly +3 more sources
Lateral Flow Biosensors for the Detection of Nucleic Acid
2013The detection of nucleic acid is of central importance for the diagnosis of genetic diseases, infectious agents, and biowarfare agents. Traditional strategies and technologies for nucleic acid detection are time-consuming and labor-intensive. Recently, isothermal strand-displacement reaction-based lateral flow biosensors have attracted a great deal of ...
Lingwen, Zeng +3 more
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IEEE Transactions on NanoBioscience, 2023
Methamphetamine is a powerful stimulant drug, the abuse of which threatens human health and social stability. Rapid and accurate quantification of methamphetamine is essential to inhibit the abuse and prevalence of methamphetamine effectively. In this paper, we present a portable fluorescence reader with upconverting nanoparticle-labeled lateral flow ...
Lei Huang +5 more
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Methamphetamine is a powerful stimulant drug, the abuse of which threatens human health and social stability. Rapid and accurate quantification of methamphetamine is essential to inhibit the abuse and prevalence of methamphetamine effectively. In this paper, we present a portable fluorescence reader with upconverting nanoparticle-labeled lateral flow ...
Lei Huang +5 more
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A lateral flow biosensor for the detection of human pluripotent stem cells
Analytical Biochemistry, 2013A lateral flow biosensor based on immunoassay has been developed for the detection of human stem cells for the first time. Antibody specific for a human stem cell surface antigen, SSEA-4, is coated onto gold nanoparticles, whereas antibody against another human pluripotent stem cell surface antigen, SSEA-3, is immobilized on the test zone of the NC ...
Wei, Wu +4 more
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Paper-Based Biosensors with Lateral/Vertical Flow Assay
2020The lateral flow assay (LFA), which is a simple paper-based device for the detection and analysis of disease, is now the most predominant diagnostic platform in point-of-care (POC) markets [1, 2, 3, 4]. This market-dominating power stems from the unique characteristics of the LFA: low cost, portability, versatility, easy use, free of other instruments,
Dohwan Lee, Jeong Hoon Lee
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A Lateral Flow Biosensor for the Detection of Single Nucleotide Polymorphisms
2017A lateral flow biosensor (LFB) is introduced for the detection of single nucleotide polymorphisms (SNPs). The assay is composed of two steps: circular strand displacement reaction and lateral flow biosensor detection. In step 1, the nucleotide at SNP site is recognized by T4 DNA ligase and the signal is amplified by strand displacement DNA polymerase ...
Lingwen, Zeng, Zhuo, Xiao
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