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A lateral flow biosensor based on gold nanoparticles detects four hemorrhagic fever viruses
Analytical Methods, 2020The pathogen of viral hemorrhagic fever (VHF), which is harmful to human health, is a hemorrhagic fever virus.
Jin Zhao +4 more
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A Lateral Flow Biosensor for the Detection of Single Nucleotide Polymorphisms
2017A lateral flow biosensor (LFB) is introduced for the detection of single nucleotide polymorphisms (SNPs). The assay is composed of two steps: circular strand displacement reaction and lateral flow biosensor detection. In step 1, the nucleotide at SNP site is recognized by T4 DNA ligase and the signal is amplified by strand displacement DNA polymerase ...
Lingwen, Zeng, Zhuo, Xiao
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An enzyme-amplified lateral flow strip biosensor for visual detection of MicroRNA-224
Talanta, 2016An enzyme-based dual-labeled nanoprobe is designed to fabricate a sensitive enzyme-amplified lateral flow biosensor for visual detection of mircoRNA-224 (miRNA-224). The recognition DNA probe (detection probe) and signal amplification enzyme (Horseradish peroxidase, HRP) are immobilized on gold nanoparticle (GNPs) surface, simultaneously.
Xuefei, Gao +5 more
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Lateral Flow Nucleic Acid Biosensors
2016Lateral flow nucleic acid biosensors (LFNABs) provide a variety of advantages, including being affordable, sensitive, specific, user-friendly, rapid, equipment-free, and deliverable to end users; thus, LFNABs have been very popular in biomedical, food, agriculture, environmental sciences, and so forth.
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A lateral flow biosensor for rapid detection of DNA-binding protein c-jun
Biosensors and Bioelectronics, 2011A lateral flow biosensor based on an immuno-chromatographic assay has been developed for the detection of DNA-binding proteins. The biosensor is composed of four parts: a sample pad, a conjugate pad, a strip of nitrocellulose membrane and an absorbent pad.
Zhiyuan, Fang +4 more
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Disposable Nucleic Acid Biosensors Based on Gold Nanoparticle Probes and Lateral Flow Strip
Analytical Chemistry, 2009In this article, we describe a disposable nucleic acid biosensor (DNAB) for low-cost and sensitive detection of nucleic acid samples in 15 min. Combining the unique optical properties of gold nanoparticles (Au-NP) and the high efficiency of chromatographic separation, sandwich-type DNA hybridization reactions were realized on the lateral flow strips ...
Xun, Mao +5 more
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Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020
Vaspin is a protein present in human serum that can cause type-2 diabetes, obesity, and other cardiovascular diseases. We report fluorescent upconverting nanoparticles (UCNPs)-based lateral flow biosensor for ultrasensitive detection of Vaspin. A pair (primary and secondary) of cognate aptamers was used that has duo binding with Vaspin.
Muhsin, Ali +6 more
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Vaspin is a protein present in human serum that can cause type-2 diabetes, obesity, and other cardiovascular diseases. We report fluorescent upconverting nanoparticles (UCNPs)-based lateral flow biosensor for ultrasensitive detection of Vaspin. A pair (primary and secondary) of cognate aptamers was used that has duo binding with Vaspin.
Muhsin, Ali +6 more
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Double-Enhanced Photothermal Lateral Flow Biosensor Based on Dual Gold Nanoparticle Conjugates
ACS SensorsBacterial toxins emerge as the primary triggers of foodborne illnesses, posing a significant threat to human health. To ensure food safety, it is imperative to implement point-of-care testing methods. Lateral flow biosensors (LFBs) based on gold nanoparticles (GNPs) have been commonly used for rapid detection, but their applicationis limited by low ...
Yan Huang +6 more
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A lateral flow biosensor for detection of nucleic acids with high sensitivity and selectivity
Chem. Commun., 2012A lateral flow biosensor based on isothermal strand-displacement polymerase reaction and gold nanoparticles has been developed for the visual detection of nucleic acids with a detection limit of 0.01 fM.
Puchang, Lie +4 more
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Towards All-Printed Lateral Flow Biosensors
2019Many devices in our day-to-day lives incorporate lateral flow biosensors, for example, home pregnancy test kits. These tests allow users to obtain results within 30 minutes by simply applying a few droplets of urine onto a test strip. However, these biosensors are largely manufactured using manual processes: workers cut strips (also called substrates ...
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