Results 41 to 50 of about 226,432 (265)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Effect of Humidity and Hydrophobicity on the Tribological Properties of Self-Assembled Monolayers

The Scientific World Journal, 2013
The tribological properties of two distinctive alkanethiol SAMs, 16-mercaptohexadecanoic acid (MHA) and 1-octadecanethiol (ODT), on gold substrates in various humidity conditions were examined by lateral force microscopy (LFM).
Yen-Chih Liao, William Hargrove, Brandon L. Weeks   +2 more
doaj   +1 more source

Study on the Lateral Force of the Single Lap Joint of Composite Laminates

Hangkong gongcheng jinzhan, 2018
In the composite material single lap joint structure, due to the eccentricity of the load, the lateral force is generated in the lap joint, which causes the lateral displacement of the joint and deflects the bolt.
Zhang Zhihong, Zhang Boping, Yang Jie
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

METHODOLOGY FOR ENGINEERING CALCULATION OF STABILITY COEFFICIENT AGAINST WHEEL CLIMBING ON THE RAIL

Nauka ta progres transportu, 2020
Purpose. One of the indicators of the track and rolling stock interaction, non-observance of which can result in a traffic safety violation, namely to derailment, is a condition for ensuring stability against the wheel flange climbing onto the rail head.
D. M. Kurhan, O. V. Hubar, M. O. Havrilov   +2 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Influence of Air Spring Failure on Operation Safetyfor Straddle-type Monorail Vehicle

机车电传动, 2016
The air spring rubber capsule rupture of straddle-type monorail vehicle model was established, and the safety performanceof vehicle system with air spring failure was analyzed, focusing on the overturning stability coefficient and horizontal wheel’s ...
Du Zixue, Cao Danting
doaj  

Factors Influencing Deviation Correction Capability of Automatic Vertical Drilling Tool

Shiyou jixie, 2021
Automatic vertical drilling system can solve the poor effect of traditional passive deviation control system. In order to realize effective deviation control and correction of automatic vertical drilling system, the factors influencing the deviation ...
Yang Dengwen, Zhang Kai, Chai Lin, Liu Baolin   +3 more
doaj  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source