Results 61 to 70 of about 3,156,191 (292)

The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis [PDF]

open access: yes, 2012
Recent evidence highlights the peroxisome proliferator-activated receptors (PPARs) as critical neuroprotective factors in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). To gain new mechanistic insights into the role of
Maggi, Adriana   +8 more
core   +1 more source

Effect of the Particle Size Distribution of the Ballast on the Lateral Resistance of Continuously Welded Rail Tracks

open access: yesInfrastructures
While the effect of ballast degradation on lateral resistance is noteworthy, limited research has delved into the specific aspect of ballast breakage in this context.
Jafar Chalabii   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Seismic Behaviour of Reinforced Concrete Slit Shear Walls Energy Dissipators

open access: yesBulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2010
The types of slit walls energy dissipators, from monolith or precast reinforced concrete, proposed by researchers and the seismic behaviour of these types of walls are described.
Sergiu Băetu, I. Ciongradi
doaj  

Lateral loading resistance for shell foundations [PDF]

open access: yesHBRC Journal, 2020
Shell foundations, or geometrically shaped footings, were first used as a substitute for the conventional flat shallow foundations in the nineteen fifties in Mexico, West Germany, India, China and ...
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Mechanical and Deformation Response of WJ-8B Rail Fastener Under Cyclic Lateral Loading

open access: yesBuildings
The mechanical performance of rail fasteners plays a crucial role in the track–structure interaction of high-speed railways. A reasonable lateral stiffness of the fastener system can enhance the stability and safety of train operation and prevent ...
Fengyu Zhang   +3 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

A lateral nos falares florianopolitano (PB) e portuense (PE): casos de gradiência fônica [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Linguística, Florianópolis, 2014.Esta tese teve como objetivo principal apresentar as características acústicas dos sons laterais ...
Brod, Lílian Elisa Minikel
core  

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