Results 141 to 150 of about 1,616 (166)
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Clinica Chimica Acta, 2014
The analysis of blood for β-sitosterol and campesterol is the measures of cholesterol absorption while lathosterol is a measure of cholesterol synthesis.The biological variability of β-sitosterol, campesterol, and lathosterol was measured using liquid-chromatography tandem mass spectrometry from a cohort of 25 apparently healthy subjects, where blood ...
Alan H B, Wu +3 more
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The analysis of blood for β-sitosterol and campesterol is the measures of cholesterol absorption while lathosterol is a measure of cholesterol synthesis.The biological variability of β-sitosterol, campesterol, and lathosterol was measured using liquid-chromatography tandem mass spectrometry from a cohort of 25 apparently healthy subjects, where blood ...
Alan H B, Wu +3 more
openaire +2 more sources
Int. Journal of Clinical Pharmacology and Therapeutics, 2005
Plant sterol/stanol margarines are recommended as a lipid-lowering dietary supplement in the treatment of hypercholesterolemia. Parameters predicting the individual cholesterol-lowering effect have not been elucidated so far. Therefore, we investigated the responsiveness to sitostanol-supplemented margarine in a specially selected population.From a ...
S C, Thuluva +5 more
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Plant sterol/stanol margarines are recommended as a lipid-lowering dietary supplement in the treatment of hypercholesterolemia. Parameters predicting the individual cholesterol-lowering effect have not been elucidated so far. Therefore, we investigated the responsiveness to sitostanol-supplemented margarine in a specially selected population.From a ...
S C, Thuluva +5 more
openaire +2 more sources
Journal of Chromatography B, 2011
A simple method has been developed for the simultaneous determination of lathosterol and cholesterol by high-performance liquid chromatography with electrochemical detection (HPLC-ECD). Lathosterol was found to be electrochemically oxidized and its current peak height was linearly related to the amount of lathosterol injected, ranging from 0.15 μmol/L ...
Kazuhiro, Hojo +2 more
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A simple method has been developed for the simultaneous determination of lathosterol and cholesterol by high-performance liquid chromatography with electrochemical detection (HPLC-ECD). Lathosterol was found to be electrochemically oxidized and its current peak height was linearly related to the amount of lathosterol injected, ranging from 0.15 μmol/L ...
Kazuhiro, Hojo +2 more
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Biochemistry, 2011
We performed differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopic measurements to study the effects of lathosterol (Lath) on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine (DPPC) bilayer membranes and compared our results with those previously reported for cholesterol (Chol ...
Matthew G K, Benesch +3 more
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We performed differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopic measurements to study the effects of lathosterol (Lath) on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine (DPPC) bilayer membranes and compared our results with those previously reported for cholesterol (Chol ...
Matthew G K, Benesch +3 more
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Radiobiologiia, 1991
Normal and irradiated fibrinogen, gamma-globulins, alpha- and beta-globulins and albumins of blood plasma were shown to contain squalene, lathosterol, cholesterol and some other compounds as lipid components. Radiation alteration of the total number of unsaponifiable substances and some lipid components in the individual blood plasma proteins followed ...
V I, Palamarchuk +2 more
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Normal and irradiated fibrinogen, gamma-globulins, alpha- and beta-globulins and albumins of blood plasma were shown to contain squalene, lathosterol, cholesterol and some other compounds as lipid components. Radiation alteration of the total number of unsaponifiable substances and some lipid components in the individual blood plasma proteins followed ...
V I, Palamarchuk +2 more
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European journal of clinical nutrition, 1996
The aim of the study was to determine the effect of replacing saturated fatty acids (SAFA) with polyunsaturated fatty acids (PUFA) in the diet on plasma lathosterol concentration, an index of cholesterol synthesis, in mildly hypercholesterolaemic subjects.The study was a randomised, cross-over trial.Seventy-six subjects were recruited and one dropped ...
C M, Cox +3 more
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The aim of the study was to determine the effect of replacing saturated fatty acids (SAFA) with polyunsaturated fatty acids (PUFA) in the diet on plasma lathosterol concentration, an index of cholesterol synthesis, in mildly hypercholesterolaemic subjects.The study was a randomised, cross-over trial.Seventy-six subjects were recruited and one dropped ...
C M, Cox +3 more
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Partial purification and characterization of lathosterol 5-desaturase from rat liver microsomes.
Journal of biochemistry, 1985The terminal oxidase of the NADH-dependent lathosterol 5-desaturation system was solubilized from rat liver microsomes with 2% Triton X-100, and partially purified approximately 18-fold with 19% yield after DEAE-cellulose and 6-aminohexyl-Sepharose column chromatography.
K, Honjo, T, Ishibashi, Y, Imai
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Lathosterol to cholesterol ratios in cystic fibrosis
Gastroenterology, 1998J.C. Deutsch +4 more
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Bioorganic & medicinal chemistry, 2000
The fate of 6alpha- and 6beta-hydrogens of lathosterol during the transformation into 20-hydroxyecdysone was chased by feeding [3alpha,6beta-2H2]- and [3alpha,6alpha-2H2]-lathosterols to hairy roots of Ajuga reptans var. atropurpurea. The behavior of 6beta-hydrogen, which mostly migrated to the C-5 position of 20-hydroxyecdysone, was in agreement with ...
K, Ohyama +3 more
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The fate of 6alpha- and 6beta-hydrogens of lathosterol during the transformation into 20-hydroxyecdysone was chased by feeding [3alpha,6beta-2H2]- and [3alpha,6alpha-2H2]-lathosterols to hairy roots of Ajuga reptans var. atropurpurea. The behavior of 6beta-hydrogen, which mostly migrated to the C-5 position of 20-hydroxyecdysone, was in agreement with ...
K, Ohyama +3 more
openaire +1 more source