Results 181 to 190 of about 25,828 (235)

Position Effect Variegation of Penicillium rubens Genome and Application in Heterologous Production of the Plant‐Derived Anthraquinone Physcion

Microbial Biotechnology, Volume 19, Issue 10, October 2026.
This study constructed a PiggyBac transposon mediated mutagenesis system which was used to investigate the genomic position effect on heterologous production of physcion in Penicillium ruben. This PB platform enables efficient genetic engineering for secondary metabolite production. ABSTRACT The filamentous fungus Penicillium rubens is well known as an
Meng Wu, Yushi Fu, Linqin Tang, Yongpeng Yao, Yuanyuan Pan, Gang Liu   +5 more
wiley   +1 more source

Automatic Evaluation of Small Bowel Cleanliness in Capsule Endoscopy: A Comparative Study of Four Preparations using Artificial Intelligence. [PDF]

Endosc Int Open
Nevarez A, Noorda R, Alonso-Lazaro N, Carretero C, de Frías CP, González Suárez B, Giordano A, Jiménez-García VA, Lorenzo Gonzalez L, Caunedo-Álvarez Á, Valle Muñoz J, García Vela A, Lujan-Sanchís M, Ruiz Sánchez L, Sanchez Ceballos F, Mendoza Hernández JL, García Lledó J, Nogales Rincón O, Egea Valenzuela J, Mesa López MJ, Merino Zubizarreta A, Estévez Boullosa P, Martinez-Turnes A, Bustamante-Balén M, Naranjo V, Pons Beltrán V.   +25 more
europepmc   +1 more source

GLP‐1‐Based Therapies in Type 1 Diabetes: Emerging Evidence on Cardiovascular, Renal, and Safety Outcomes

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8757-8768, October 2026.
ABSTRACT Background Individuals living with type 1 diabetes (T1D) are at increased risk for cardiovascular (CV) and renal complications, yet therapeutic strategies specifically targeting cardiorenal risk reduction in this population remain limited. The role of glucagon‐like peptide‐1 (GLP‐1)‐based therapies in T1D remains unclear.
Anastasios Tentolouris, Djordje S. Popovic, Alexandros L. Liarakos, Alexandros Briasoulis, Nikolaos Papanas, Theocharis Koufakis   +5 more
wiley   +1 more source

Editorial: New insights into the management of chronic idiopathic constipation: from physiopathology to novel therapeutic strategies

Frontiers in Pharmacology
Christian Lambiase, Christian Lambiase, Matteo Fornai, Maura Corsetti, Maura Corsetti, Massimo Bellini, Massimo Bellini   +6 more
doaj   +1 more source

Dependence-related screening positivity among regular stimulant-laxative users with chronic constipation: a multicenter prospective observational study. [PDF]

J Gastroenterol
Ishihara Y, Ihara E, Esaki M, Takahashi K, Tomita N, Dang TH, Ohira M, Horiuchi M, Uchida A, Toriumi Y, Nishizawa T, Ohkubo H, Imajo K, Oyamada S, Iwasaki T, Kurihashi T, Yamauchi A, Nakazato M, Nakajima A, Kessoku T.   +19 more
europepmc   +1 more source

Association Between CT‐Based Rectal Stool Attenuation and Activities of Daily Living in Hospitalized Older Adults

Geriatrics &Gerontology International, Volume 26, Issue 10, October 2026.
Higher rectal stool attenuation on abdominal CT was associated with lower BADL and IADL scores. This parameter may offer additional functional information from CT examinations already obtained for clinical indications. ABSTRACT Objectives To explore the association between rectal stool characteristics measured by computed tomography (CT), particularly ...
Hitoshi Komiya, Kazuhisa Watanabe, Masaaki Nagae, Hirotaka Nakashima, Chisato Fujisawa, Tomihiko Tajima, Yosuke Yamada, Hiroyuki Umegaki   +7 more
wiley   +1 more source

Constipation outcomes in children with and without autism spectrum disorder: Insights from a tertiary motility service. [PDF]

J Pediatr Gastroenterol Nutr
Khalid U, Bolia R, Bunt J, Lang R, Thapar N.   +4 more
europepmc   +1 more source

Tenapanor Beyond Phosphate: Gut Sodium Transport, Stool Transit Time, and Volume Balance in Dialysis Patients

Hemodialysis International, Volume 30, Issue 4, Page 689-697, October 2026.
ABSTRACT Introduction Tenapanor, a minimally absorbed intestinal NHE3 inhibitor approved for hyperphosphatemia in dialysis, lowers phosphate and reduces intestinal sodium absorption. Its sodium–water signal may have implications beyond phosphate but remains poorly separated from diarrhea‐mediated losses and dialysis prescription artifacts. Methods This
Lucas Maciel de Almeida Corrêa, Luiggi Kevin Virgino Brandão, Clara Belo Gamon Santiago, Alexandre de Assis Barbosa, Gabriel Rian Mazur, Gabriel Costa de Santana, Yan Roberth Delmiro Silva, Letícia Esteves Dante, Ivan Felipe Dutra Júnior   +8 more
wiley   +1 more source

Impact of constipation on patients with schizophrenia and depression: an internet-based survey (CONSIDER survey). [PDF]

Front Psychiatry
Hori H, Takeuchi H, Yoneda S, Shin T, Shimada Y, Umeyama M, Ueno M, Takekita Y.   +7 more
europepmc   +1 more source

Does Current United Kingdom Childhood Cancer Research Address the James Lind Alliance Children's Cancer Priority Setting Partnership Priorities? A Grant Mapping Study

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Introduction The James Lind Alliance Children's Cancer Priority Setting Partnership identified 23 key research topics, as defined by children, survivors, families, carers, and professionals. Funders have expressed commitment to ensuring all priorities are addressed.
Alison Bish, Faith Gibson, Alexandra Brownsdon, Julia Chisholm, Jenny Harris, Rachel Hollis, Bob Phillips, Susie Aldiss   +7 more
wiley   +1 more source