Results 101 to 110 of about 3,044,337 (312)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Droplet impact on a thin fluid layer

open access: yes, 2005
The initial stages of high-velocity droplet impact on a shallow water layer are described, with special emphasis given to the spray jet mechanics. Four stages of impact are delineated, with appropriate scalings, and the successively more important ...
Purvis, R   +12 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Serologic prevalence of ornithobacterium rhinotracheale infection in commercial layers [PDF]

open access: yesEurasian Journal of Veterinary Sciences
Aim: The purpose of this study was to determine the serological prevalence of Ornithobacterium (O.) rhinotracheale infections in commercial layers. Materials and Methods: A total of 650 blood serum samples were collected from 26 different layer flocks ...
Zeki Aras   +2 more
doaj  

Control of shock-induced boundary layer separation at supersonic speeds

open access: yes, 2007
PhDThe results of a systematic experimental investigation into the effects that Sub- Boundary Layer Vortex Generators (SBVGs) have on reducing normal shock-induced turbulent boundary layer separation are presented.
Cohen, Giel S, Cohen, Giel S.
core  

Facilitating mass transport in gas diffusion layer of PEMFC by fabricating micro-porous layer with dry layer preparation

open access: yes, 2008
For a proton exchange membrane fuel cell (PEMFC), dry layer preparation was optimized and applied to fabricate a micro-porous layer (MPL) for a gas diffusion layer (GDL).
Xu, Haifeng   +4 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

THE STUDY OF OF PROCESS DRYING COOKED RICE IN A BOILING BED

open access: yesСовременная наука и инновации, 2022
The research of process of drying of cooked rice in the boiling layer was found optimal modes of drying and hydrothermal processing of grain, allowing to reduce the specific energy consumption, increase the capacity of the dryer and improve the quality ...
Oksana A. Klimenchuk   +1 more
doaj  

WATER PUMPING CONTROL FOR INCREASING OF FIELDS DEVELOPMENT EFFICIENCY, PROTECTION OF EARTH'S BOWELS AND ENVIRONMENT

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2016
In any complex system, in which the work is performed for the transformation and transmission losses and unproductive work are inevitably arise. The reservoir pressure maintenance system, the magnitude of these losses could be substantial, providing a ...
R. Z. Nurgaliev   +4 more
doaj   +1 more source

Layer-by-Layer Thinning of PdSe2 Flakes via Plasma Induced Oxidation and Sublimation

open access: yes, 2020
Controlled O2/Ar plasma exposure and subsequent low temperature inert atmosphere annealing of chemical vapor deposition (CVD) grown PdSe2 flakes etch PdSe2 layer-by-layer in an atomic layer etching-like (ALE) process.
Yiyi Gu (6742898)   +11 more
core   +1 more source

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