Results 111 to 120 of about 6,179,921 (285)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Susceptibility and cecal microbiota alteration to Eimeria-infection in Yellow-feathered broilers, Arbor Acres broilers and Lohmann pink layers

open access: yesPoultry Science
: Coccidiosis, which is caused by Eimeria species, results in huge economic losses to the poultry industry. Arbor Acres (AA) broilers and yellow-feathered broilers are the dominant broilers in northern and southern China, respectively.
Shiqi Du   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Offset fields in perpendicularly magnetized tunnel junctions

open access: yes, 2019
We study the offset fields affecting the free layer of perpendicularly magnetized tunnel junctions. In extended films, the free layer offset field results from interlayer exchange coupling with the reference layer through the MgO tunnel oxide.
Carpenter, R.   +6 more
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Serologic prevalence of ornithobacterium rhinotracheale infection in commercial layers [PDF]

open access: yesEurasian Journal of Veterinary Sciences
Aim: The purpose of this study was to determine the serological prevalence of Ornithobacterium (O.) rhinotracheale infections in commercial layers. Materials and Methods: A total of 650 blood serum samples were collected from 26 different layer flocks ...
Zeki Aras   +2 more
doaj  

Chirality- and thickness-dependent thermal conductivity of few-layer graphene: a molecular dynamics study

open access: yes, 2011
The thermal conductivity of graphene nanoribbons (layer from 1 to 8 atomic planes) is investigated by using the nonequilibrium molecular dynamics method.
Ai, Bao-Quan   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

PLUTONIC STRUCTURE OF THE DEEP-SEA BASINS IN THE SEA OF OKHOTSK REGION

open access: yesГеодинамика и тектонофизика, 2018
The original continental crust of the deep-sea basins in the Sea of Okhotsk region was considerably reworked by tectonic and magmatic processes, whereby it has become substantially denser while less thick.
V. P. Semakin   +2 more
doaj   +1 more source

Chimera states in a multilayer network of coupled and uncoupled neurons

open access: yes, 2017
We study the emergence of chimera states in a multilayer neuronal network, where one layer is composed of coupled and the other layer of uncoupled neurons.
Ghosh, Dibakar   +2 more
core   +1 more source

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