Results 121 to 130 of about 6,179,921 (285)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Spin Fluctuations in Magnetically Coupled Bi-layer Cuprates
, 1996 We propose a possible mechanism of pseudo spin gap anomaly(PSGA) in magnetically coupled bi-layer cuprates without any fermion pairing instability. In our proposal PSGA does not necessarily require the spin-charge separation or the breakdown of the Fermi
J. Kishine +5 more
core +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
THE STUDY OF OF PROCESS DRYING COOKED RICE IN A BOILING BED
Современная наука и инновации, 2022 The research of process of drying of cooked rice in the boiling layer was found optimal modes of drying and hydrothermal processing of grain, allowing to reduce the specific energy consumption, increase the capacity of the dryer and improve the quality ...
Oksana A. Klimenchuk +1 more
doaj
Известия высших учебных заведений: Нефть и газ, 2016 In any complex system, in which the work is performed for the transformation and transmission losses and unproductive work are inevitably arise. The reservoir pressure maintenance system, the magnitude of these losses could be substantial, providing a ...
R. Z. Nurgaliev +4 more
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Applied SciencesBackground: Fluoride is vital in dentistry for caries prevention, enhancing remineralization, and inhibiting bacteria. Incorporating fluoride into restorative materials like glass-ionomer cements, compomers, and giomers has significantly increased ...
Dominik Tokarczuk +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source