Results 61 to 70 of about 1,988,983 (304)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Diagnosis of Gallibacterium Anatis in Layers: First Report in Turkey [PDF]

open access: yesBrazilian Journal of Poultry Science, 2019
Gallibacterium anatis, a member of the Pasteurellaceae family, leads to decrease in egg-production, animal welfare and increase in mortality. This study aimed to diagnose G.
S Yaman, O Sahan Yapicier
doaj   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure and properties of Ni22Cr10Al1Y coatings deposited by the vacuum plasma spray process / Структура и свойства покрытия Ni22Cr10Al1Y нанесенного методом вакуумного плазменного напыления / Struktura i svojstva prevlake Ni22Cr10Al1Y deponovane vakuum-plazma-sprej procesom

open access: yesVojnotehnički Glasnik, 2017
In this study, the aim was to deposit layers of the Ni22Cr10Al1Y coating using the vacuum plasma spray process to protect gas turbine engine components from oxidation and high-temperature corrosion.
Mihailo R. Mrdak
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

IMPACT OF PHYTASE SUPPLEMENTATION ON THE CALCIUM AND PHOSPHOROUS RETENTION IN HIGH PRODUCING LAYERS [PDF]

open access: yesPoljoprivreda, 2007
The calcium and phosphorous retention of layers was evaluated at different production levels (45 - 75 - 95 % of final production peak) with Hy-Line Brown hybrid layers during the first twelve weeks of the laying cycle. 32 layers evenly distributed over 4
J. Tossenberger   +4 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Layer by layer, spin by spin [PDF]

open access: yesScience Advances
There comes a time in every academic life when the level of responsibility becomes terrifying. In my five years at Science Advances, first as an associate and then as a deputy editor, there was always a benevolent superpower at the top – it had never intervened but its existence created a peace of mind.
openaire   +2 more sources

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