Results 71 to 80 of about 1,050,141 (264)
AnimalsGiven the significant environmental consequences of current poultry feed practices and the heavy dependence of the European Union on imported soybeans, studying alternatives is crucial. This study evaluated the potential benefits of using locally sourced
Ana Montalbán +8 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Nature Communications80 pages, 33 figures; v2 substantial changes to improve ...
Dominic J. Williamson, Nouédyn Baspin
openaire +4 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Characterisation of Niobium Carbide Coating Obtained by Chemical Vapour Deposition
The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2010 The experiments conducted to obtain thin layer of carbide by the vapour chemical deposition method have followed an original path to make NbC directly in the working room thus avoiding the import of these hazardous substances.
Stela CONSTANTINESCU
doaj
GENETIC DETERMINISM OF THE REPRODUCTION TRAITS IN A PLYMOUTH ROCK LINE
Scientific Papers Animal Science and Biotechnologies, 2023 The heritability of the studied traits was below 0.2 in four traits (age at first egg, body weight, eggs produced during the control period, laying percentage during the control period); only egg weight having a higher heritability, 0.698.
RODICA PELMUS +2 more
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
NEWCASTLE DISEASE VIRUS IN THE INTESTINAL CONTENTS OF BROILERS AND LAYERS [PDF]
Pakistan Veterinary Journal, 2004 Two hundred intestines pieces (100 each of broilers and layers) of about 8 cm length were collected from the poultry sale shops in Faisalabad city. These pieces were opened, scratched and vigorously shaken into sterilized normal saline, the suspension ...
S. Ullah, M. Ashfaque, S.U. Rahman, M. Akhtar and A. Rehman
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source