Results 71 to 80 of about 1,988,983 (304)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Global and Koopman modes analysis of sound generation in mixing layers [PDF]
, 2013 It is now well established that linear and nonlinear instability waves play a significant role in the noise generation process for a wide variety of shear flows such as jets or mixing layers.
X. Gloerfelt +7 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 1997 Negli anni 1997-1998 sono stato dipendente del Fermi National Accelerator Laboratory e ho contruito alla progettazione e costruzione del rivelatore successivamente installato nell'esperimento CDF per la presa dati "Run II" del Tevatron degli anni 2001 ...
DONATI, SIMONE +1 more
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Improving neural network’s robustness on tabular data with D-layers
, 2023 Artificial neural networks ($${{{\texttt {ANN}}}}$$ ANN ) are widely used machine learning models. Their widespread use has attracted a lot of interest in their robustness. Many studies show that ’s performance can be highly
Nayyar Zaidi (13086885) +3 more
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
The Journal of Logic Programming, 1999 Summary: Modes were introduced in logic programming to differentiate the input arguments of a predicate from its output arguments. This information can be used for verifying the most diverse properties of logic programs, notably absence of run-time errors and absence of deadlocks in presence of delay declarations.
Sandro Etalle, Maurizio Gabbrielli
openaire +8 more sources
Short-scale break-up in unsteady interactive layers: Local development of normal pressure gradients and vortex wind-up [PDF]
, 1998 Following the finite-time collapse of an unsteady interacting boundary layer (step 1), shortened length and time scales are examined here in the near-wall dynamics of transitional-turbulent boundary layers or during dynamic stall.
Bowles, RI +7 more
core +1 more source