Results 41 to 50 of about 345,303 (283)

A biorational approach for management of key plant pathogens

The Indian Journal of Agricultural Sciences, 2015
The antifungal potential of solvent extracts of four plants, viz. Polyalthia longifolia (Sonn.) Thw. (PL), Paederia foetida (PF), Limonia acidissima L. (LA) and Balanites aegyptiaca (L.) Del.
SUMITRA ARORA, NAVIN KUMAR MOGHA, TULSI BHARDWAJ, VIKRANT SAHU, SUNIL CHANDRA DUBEY   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Advanced Positioning and Location based services in 4G Mobile-IP Radio Access Networks [PDF]

, 2004
2004 IEEE 15TH IEEE International Symposium on personal, indoor and mobile radio communications (PIMRC 2004), Barcelona, Spain, 5-8 september 2004.This paper proposes an evolved architecture from 3G networks to provide basic and advanced positioning ...
Montilla Bravo, Alberto, Moreno Novella, José Ignacio, Soto, Ignacio   +2 more
core   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Application of artificial neural networks and multiple linear regression on local bond stress equation of UHPC and reinforcing steel bars

Scientific Reports, 2021
We investigated the use of an Artificial Neural Network (ANN) to predict the Local Bond Stress (LBS) between Ultra-High-Performance Concrete (UHPC) and steel bars, in order to evaluate the accuracy of our LBS equation, proposed by Multiple Linear ...
Ahad Amini Pishro, Shiquan Zhang, Dengshi Huang, Feng Xiong, WeiYu Li, Qihong Yang   +5 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Lipid Body Organelles within the Parasite Trypanosoma cruzi: A Role for Intracellular Arachidonic Acid Metabolism. [PDF]

PLoS ONE, 2016
Most eukaryotic cells contain varying amounts of cytosolic lipidic inclusions termed lipid bodies (LBs) or lipid droplets (LDs). In mammalian cells, such as macrophages, these lipid-rich organelles are formed in response to host-pathogen interaction ...
Daniel A M Toledo, Natália R Roque, Lívia Teixeira, Erix A Milán-Garcés, Alan B Carneiro, Mariana R Almeida, Gustavo F S Andrade, Jefferson S Martins, Roberto R Pinho, Célio G Freire-de-Lima, Patrícia T Bozza, Heloisa D'Avila, Rossana C N Melo   +12 more
doaj   +1 more source

Vegetable Fertility Management Trial [PDF]

, 2015
Many organic vegetable producers have been relying heavily on livestock composts as a source of fertility on farm. Often, high rates of compost are applied to meet the nitrogen (N) needs of crops.
Calderwood, Lily, Cummings, Erica, Darby, Heather, Gupta, Abha, Post, Julian, Zieglar, Sara   +5 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source