Results 61 to 70 of about 346,399 (224)

Transcriptome data of cultivated tetraploid and hexaploid wheat variety during grain development

Data in Brief, 2019
Wheat is a major food crop and an important component of human diet throughout the world. There are two major types of cultivated wheat; one is tetraploid durum (pasta) wheat and another one is hexaploid bread wheat.
Pranab Kumar Mandal, Shubham Rai, Megha Kaushik, Subodh Kumar Sinha, Rajesh Kumar Gupta, Anju Mahendru   +5 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

A hybrid evolutionary and structural method for AI-guided peptide inhibitor design using AlphaFold and Rosetta

Scientific Reports
Peptide inhibitors represent a promising class of antiviral therapeutics, offering several advantages over traditional small-molecule drugs, including low toxicity, high specificity, and biocompatibility.
Frederico Chaves Carvalho, Diego Mariano, Luana Bastos, Ana Paula de Abreu, Rafael Pereira Lemos, Sheila Cruz Araújo, Lucas Moraes dos Santos, Raquel Cardoso de Melo-Minardi   +7 more
doaj   +1 more source

The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer’s dementia in older persons

Acta Neuropathologica Communications, 2021
Lewy bodies (LBs) and limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) are common in older persons and associated with cognitive impairment.
Sonal Agrawal, Lei Yu, Sukriti Nag, Konstantinos Arfanakis, Lisa L. Barnes, David A. Bennett, Julie A. Schneider   +6 more
doaj   +1 more source

Spatial ability, urban wayfinding and location-based services:a review and first results [PDF]

, 2004
Location-Based Services (LBS) are a new industry at the core of which are GISand spatial databases. With increasing mobility of individuals, the anticipatedavailability of broadband communications for mobile devices and growingvolumes of location ...
Li, C
core  

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Lipid bubbles combined with low-intensity ultrasound enhance the intratumoral accumulation and antitumor effect of pegylated liposomal doxorubicin in vivo

Drug Delivery, 2021
Pegylated liposomal doxorubicin (PLD) is a representative nanomedicine that has improved tumor selectivity and safety profile. However, the therapeutic superiority of PLD over conventional doxorubicin has been reported to be insignificant in clinical ...
Inoru Yokoe, Daiki Omata, Johan Unga, Ryo Suzuki, Kazuo Maruyama, Yoshiharu Okamoto, Tomohiro Osaki   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Vegetable Fertility Management Trial [PDF]

, 2015
Many organic vegetable producers have been relying heavily on livestock composts as a source of fertility on farm. Often, high rates of compost are applied to meet the nitrogen (N) needs of crops.
Calderwood, Lily, Cummings, Erica, Darby, Heather, Gupta, Abha, Post, Julian, Zieglar, Sara   +5 more
core   +1 more source

MusA: Using Indoor Positioning and Navigation to Enhance Cultural Experiences in a museum [PDF]

, 2013
In recent years there has been a growing interest into the use of multimedia mobile guides in museum environments. Mobile devices have the capabilities to detect the user context and to provide pieces of information suitable to help visitors discovering ...
Alciatore, Andrea Bottino, Andrea Martina, Baharuddin, Bellotti, Bihler, Bitgood, Bitgood, Bruno, Chen, Chen, Csikszentmihalyi, Dean, Douglas, Emmanouilidis, Falk, Faugeras, Fischler, Ghiani, Ghiani, Giovanni Malnati, Guillemaut, Hausmann, Hausmann, Hsu, Huang, Irene Rubino, Iurgel, Jetmir Xhembulla, Kang, Kenteris, Maybank, Mulloni, Packer, Proctor, Rounds, Russo, Ruíz, Schweighofer, Serrell, Stock, Traum, Tsai, Veron, Wang, Yanying, Zhang, Zhang   +47 more
core   +3 more sources