Results 41 to 50 of about 346,399 (224)
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openaire +3 more sources
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Who actually wants to use ‘the killer app’? Perceptions of location based services in the young and old [PDF]
This paper describes the results of two qualitative case studies that assessed the perceptions of Location Based Services (LBS) with two UK user groups: a family with a behaviour-disordered teenager, and a group of older adults.
Thomas, Lisa
core
Structure of sunspot light bridges in the chromosphere and transition region
Light bridges (LBs) are elongated structures with enhanced intensity embedded in sunspot umbra and pores. We studied the properties of a sample of 60 LBs observed with the Interface Region Imaging Spectrograph (IRIS). Using IRIS near- and far-ultraviolet
Rezaei, Reza
core +1 more source
Advanced Positioning and Location based services in 4G Mobile-IP Radio Access Networks [PDF]
2004 IEEE 15TH IEEE International Symposium on personal, indoor and mobile radio communications (PIMRC 2004), Barcelona, Spain, 5-8 september 2004.This paper proposes an evolved architecture from 3G networks to provide basic and advanced positioning ...
Montilla Bravo, Alberto +2 more
core +3 more sources
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
News reports of the last few years indicated that several intelligence agencies are able to monitor large networks or entire portions of the Internet backbone. Such a powerful adversary has only recently been considered by the academic literature.
Ateniese, Giuseppe +4 more
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
We investigated the use of an Artificial Neural Network (ANN) to predict the Local Bond Stress (LBS) between Ultra-High-Performance Concrete (UHPC) and steel bars, in order to evaluate the accuracy of our LBS equation, proposed by Multiple Linear ...
Ahad Amini Pishro +5 more
doaj +1 more source

