Results 71 to 80 of about 345,303 (283)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Development of Location-Based Services in Smart Systems: A Literature Review

open access: yesEmitor: Jurnal Teknik Elektro
Location-Based Services (LBS) are technologies that utilize user location data to provide relevant location-based information. This study aims to examine various LBS applications in smart systems through a review of previous literature.
Mhd. Hanafi, Firdaus
doaj   +1 more source

Analisis penentuan LBS sebagai upaya melokalisir daerah gangguan di penyulang Pandan Landung ULP Kebonagung PT. PLN (Persero) UP3 Malang

open access: yesJurnal Eltek, 2020
Penyulang Pandan Landung merupakan penyulang dengan sistem radial. Dengan sistem radial ini, saat terjadi gangguan dapat diminimalisir dengan penempatan LBS, sedangkan untuk manuver dengan penyulang lain perlu diperhatikan dahulu beban yang dapat ...
Rohmanita Duanaputri   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Brief, Aerobic-surge Exercises for Effective Weight Loss: a Randomized, Controlled Trial [PDF]

open access: yes, 2019
Background: Obesity is a growing disease and a consistently effective protocol is needed to reduce this epidemic. The purpose of this study was to determine if a frequent, brief (2-minute) high intensity aerobic exercise (≥75% max HR) was effective in ...
Curran, Sarah, Willis, F. Buck
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Roadside Intelligence: Efficient Channel Estimation for IRS-Aided mmWave Vehicular Communication

open access: yesIEEE Access
Fifth-generation(5G) and beyond communication systems, assisted by Intelligent Reflecting Surfaces (IRS), often encounter hindrances such as unreliable connections, high energy usage, and prolonged latency.
S. Nandan, M. Abdul Rahiman
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Trajectory and Policy Aware Sender Anonymity in Location Based Services

open access: yes, 2012
We consider Location-based Service (LBS) settings, where a LBS provider logs the requests sent by mobile device users over a period of time and later wants to publish/share these logs.
Deutsch, Alin   +3 more
core   +1 more source

Multi-level indoor navigation ontology for high assurance location-based services [PDF]

open access: yes, 2017
© 2017 IEEE. Indoor navigation will become an importantapplication on a smartphone for Location-Based Service (LBS). An indoor navigation system should work under normalcircumstances and during emergencies, such as fires, during abuilding power shut down,
Khruahong, S   +3 more
core   +1 more source

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