Results 51 to 60 of about 24,164 (284)

3D evaluation of the lamina cribrosa with swept-source optical coherence tomography in normal tension glaucoma. [PDF]

open access: yesPLoS ONE, 2015
PURPOSE:Although the lamina cribrosa (LC) is the primary site of axonal damage in glaucoma, adequate methods to image and measure it are currently lacking.
Kazuko Omodaka   +9 more
doaj   +1 more source

Line‐field confocal optical coherence tomography, a novel non‐invasive tool for the diagnosis of onychomycosis [PDF]

open access: yes
Background and objectives Onychomycosis is common and important to distinguish from other nail diseases. Rapid and accurate diagnosis is necessary for optimal patient treatment and outcome.
Daxenberger, Fabia   +10 more
core   +2 more sources

Differential Item Functioning on the Patient Health Questionnaire 8 by Disease Subtype, Language, Sex, and Age Among People With Systemic Sclerosis: A Scleroderma Patient‐Centered Intervention Network Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu   +110 more
wiley   +1 more source

Real‐world Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, Accepted Article.
Objectives Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), yet the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to: 1) identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Assessment of atopic dermatitis in all phototypes using line‐field confocal optical coherence tomography (LC‐OCT) and reflectance confocal microscopy (RCM)

open access: yesJEADV Clinical Practice
Background Theclinical presentation of atopic dermatitis (AD) varies in different skin phototypes and has been evaluated previously using reflectance confocal microscopy (RCM).
Samantha Ouellette   +5 more
doaj   +1 more source

Measurement of optical scattering properties using line-field confocal optical coherence tomography (LC-OCT)

open access: yesBiomedical Applications of Light Scattering XII, 2022
Line-field confocal optical coherence tomography (LC-OCT) is an imaging technique that combines the principles of time-domain OCT and reflectance confocal microscopy (RCM). LC-OCT was designed to generate threedimensional (3D) morphological images of the skin, in vivo, with a spatial resolution of ∼ 1 µm.
Waszczuk, Léna   +3 more
openaire   +1 more source

The association of physical function with psychosocial patient‐reported outcomes in people with systemic lupus erythematosus

open access: yesArthritis Care &Research, Accepted Article.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts [Approaches to Positive, Patient‐centered Experiences of Aging with Lupus (APPEAL) and California Lupus Epidemiology Study
Mrinalini Dey   +8 more
wiley   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

open access: yesAdvanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang   +13 more
wiley   +1 more source

Line-field confocal optical coherence tomography: is one hour of training sufficient for diagnosing basal cell carcinoma? [PDF]

open access: yes
Background/Objectives: Basal cell carcinoma (BCC) is the most common malignancy, characterised by local invasiveness and the potential for tissue destruction. Diagnosing BCC can be challenging, particularly for less experienced dermatologists. Line-field
Barbarossa L.   +9 more
core   +1 more source

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