Results 61 to 70 of about 24,164 (284)

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Optical Coherence Tomography Imaging of the Lamina Cribrosa: Structural Biomarkers in Nonglaucomatous Diseases

Journal of Ophthalmology, 2021
The lamina cribrosa (LC) is an active structure that responds to the strain by changing its morphology. Abnormal changes in LC morphology are usually associated with, and indicative of, certain pathologies such as glaucoma, intraocular hypertension, and ...
Alice Paulo, Pedro G. Vaz, Danilo Andrade De Jesus, Luisa Sánchez Brea, Jan Van Eijgen, João Cardoso, Theo van Walsum, Stefan Klein, Ingeborg Stalmans, João Barbosa Breda   +9 more
doaj   +1 more source

Automatic Quantification of Anterior Lamina Cribrosa Structures in Optical Coherence Tomography Using a Two-Stage CNN Framework

Sensors, 2021
In this study, we propose a new intelligent system to automatically quantify the morphological parameters of the lamina cribrosa (LC) of the optical coherence tomography (OCT), including depth, curve depth, and curve index from OCT images.
Md Habibur Rahman, Hyeon Woo Jeong, Na Rae Kim, Dae Yu Kim   +3 more
doaj   +1 more source

A-405 - The basal cell carcinoma-one-stop-shop-study [Abstract] [PDF]

Background: The treatment of basal cell carcinomas (BCCs) poses significant challenges due to the invasive, time-intensive and costly nature of margin mapping techniques such as Mohs micrographic surgery.[1][2] To address these limitations, we developed ...
Deußing, M., Fünfer, Kristina, Mayer, Oliver, Mozaffari, M., Sattler, E., Schlingmann, S., Schuh, Sandra, Welzel, Julia, Wirsching, Hanna   +8 more
core   +1 more source

Cromossomo Y na síndrome de Turner: revisão da literatura [PDF]

, 2009
Turner syndrome (TS) is one of the most common types of aneuploidy among humans, and is present in 1:2000 newborns with female phenotype. Cytogenetically, the syndrome is characterized by sex chromosome monosomy (45,X), which is present in 50-60% of the ...
Bianco, Bianca Alves Vieira, Eça, Lilian Piñero, Guedes, Alexis Dourado, Lipay, Monica Vannucci Nunes, Oliveira, Rose Mary Rocco de, Verreschi, Ieda Therezinha do Nascimento   +5 more
core   +2 more sources

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

The Usefulness of Line-Field Confocal Optical Coherence Tomography in Monitoring Epidermal Changes in Atopic Dermatitis in Response to Treatment: A Pilot Study

Diagnostics
Background: Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Due to its high prevalence, considerable morbidity, and chronicity, there is a need for the accurate in vivo evaluation of treatment efficacy.
Zuzanna Dryżałowska, Leszek Blicharz, Agnieszka Michalczyk, Jan Koscian, Małgorzata Maj, Joanna Czuwara, Lidia Rudnicka   +6 more
doaj   +1 more source

Hypopigmentation as a diagnostic clue in primary extramammary Paget disease: Case report and short literature review [PDF]

, 2023
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Bazzacco, Giulia, Cavallo, Francesco, Conforti, Claudio, Di Meo, Nicola, Mazzoletti, Vanessa, Sonego, Benedetta, Zacchi, Alberto, Zalaudek, Iris, Zelin, Enrico   +8 more
core   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Morphological features of the human lingual mucosa assessed by line-field confocal optical coherence tomography

Folia Morphologica
BACKGROUND: Line-field confocal optical coherence tomography (LC-OCT) is an emerging optical imaging technique combining vertical OCT-like sections with confocal en face imaging at micrometer-scale resolution.
Yann Lelonge, Julie Chauvel Picard, Asimakis Asimakopoulos, Florian Camy, Jonas Ogen, Stephane Avril, Jean-Luc Perrot   +6 more
doaj   +1 more source