Results 161 to 170 of about 60,310 (255)

Mass Spectrometry Quantification of Epigenetic Changes: A Scoping Review for Cancer and Beyond. [PDF]

Int J Mol Sci
Comito R, Mannaioli A, Msemwa APL, Bravi F, Zunarelli C, Negri E, Porru E, Violante FS.   +7 more
europepmc   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

PROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan, Clinton J. Bradfield, Sandhini Saha, Sung Hwan Yoon, Iain D. C. Fraser, Aleksandra Nita‐Lazar   +5 more
wiley   +1 more source

Stable Carbon Isotope Analysis of Perfluorooctanoic Acid (PFOA) by Microflow-High Pressure Liquid Chromatography-Orbitrap Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Wojtal PK, Davidheiser-Kroll B, Lane CS, Mead RN.   +3 more
europepmc   +1 more source

Coupling CZE, Liquid‐Phase Ion Mobility, to MS/MS for Quantitative Top‐Down Proteomics: Revealing Significant Proteoform Differences Between Healthy and Alzheimer's Disease Brains

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani, Fei Fang, Scott E. Counts, Liangliang Sun   +3 more
wiley   +1 more source

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

PROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren, Kenneth Weke, Darryl Hardie, Mariya I. Goncheva, Ted Hupp, Javier Antonio Alfaro, Helena Pětrošová, David R. Goodlett   +7 more
wiley   +1 more source

Q-marker identification strategies in traditional Chinese medicines: a systematic review of research from 2020 to 2024. [PDF]

Front Med (Lausanne)
Tran KN, Mac GL, Munni YA, Yang IJ.
europepmc   +1 more source

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

PROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim, Jiraphorn Issara‐Amphorn, Sung Hwan Yoon, Anirban Banerjee, Aleksandra Nita‐Lazar   +4 more
wiley   +1 more source

Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS

PROTEOMICS, EarlyView.
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor, Austin Lipinski, Paul R. Langlais, Jacob C. Schwartz   +3 more
wiley   +1 more source

Deep Proteomic Profiles of the Antarctic Diatom Fragilariopsis Cylindrus Under Varying Iron and Manganese Conditions

PROTEOMICS, EarlyView.
ABSTRACT Fragilariopsis cylindrus is a key diatom in the Southern Ocean, where low iron and manganese availability constrain primary production and biogeochemical activity. The molecular mechanisms used by polar diatoms, including F. cylindrus, to cope with trace metal limitations remain largely unexplored.
Loay J. Jabre, Elden Rowland, J. Scott P. McCain, Erin M. Bertrand   +3 more
wiley   +1 more source

Integrated GC-MS and UPLC-Q-Orbitrap MS untargeted metabolomics for the comprehensive identification of metabolites and characterization of metabolic pathways in key tissues of <i>Cinnamomum cassia</i>. [PDF]

Food Chem X
Yao S, Long L, Zhu Y, Chen J, Chen L, Li L, Huang D, Ming R, Huang R, Xiao J.   +9 more
europepmc   +1 more source