Results 171 to 180 of about 91,527 (300)

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

PROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren, Kenneth Weke, Darryl Hardie, Mariya I. Goncheva, Ted Hupp, Javier Antonio Alfaro, Helena Pětrošová, David R. Goodlett   +7 more
wiley   +1 more source

Higher-Throughput Proteome Profiling Enabled by Parallelized Pre-Accumulation and Optimized Ion Processing in the Orbitrap Astral Zoom Mass Spectrometer. [PDF]

Mol Cell Proteomics
Guzman UH, Rykær M, Hendriks IA, Stewart H, Denisov E, Hagedorn B, Petzoldt J, Kreutzmann A, Mueller Y, Arrey TN, Colonius I, Østergaard O, Koenig C, Kraegenbring J, Fort KL, Couzijn E, Hauschild JP, Hermanson D, Zabrouskov V, Hock C, Damoc E, Olsen JV.   +21 more
europepmc   +1 more source

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

PROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim, Jiraphorn Issara‐Amphorn, Sung Hwan Yoon, Anirban Banerjee, Aleksandra Nita‐Lazar   +4 more
wiley   +1 more source

Proteomic Characterization of AS1411 Reveals ATP6AP1 as a Mediator of Triple‐Negative Breast Cancer Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae, Yun‐Jeong Seo, Eun‐Bi Kim, Hyoung‐Min Park, I‐Hsuan Liu, J. Eugene Lee, Jae‐Young Kim   +6 more
wiley   +1 more source

Decoding the Metabolic Signatures of Neurodegeneration Diseases: Advances in Mass Spectrometry-Based Metabolomics. [PDF]

Metabolites
Hakim MA, Li L.
europepmc   +1 more source

Comparison of In‐Gel and SP3 Based Sample Preparation Protocols for LC‐MS/MS Based Proteomics

PROTEOMICS, EarlyView.
ABSTRACT Sensitivity, robustness, and reproducibility of sample preparation are main determinants of data quality in bottom‐up mass spectrometry‐based proteomics. To this end, in‐gel protein clean‐up and digestion has been used for decades and is characterized by its robustness and compatibility with harsh lysis conditions.
Luisa Schwarzmüller, Dario Frey, Piotr Zadora, Martin Schneider, Stefan Wiemann, Dominic Helm   +5 more
wiley   +1 more source

Proteomic insights into the invasiveness and tumor progression of non-functioning pituitary adenomas: A scoping review. [PDF]

J Neuroendocrinol
Skoglund T, Köster L, Thorsell A, Ragnarsson O, Johannsson G, Hallén T.   +5 more
europepmc   +1 more source

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

PROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà, Loredana Leggio, Greta Paternò, Elena Giusto, Laura Civiero, Vincenzo Cunsolo, Silvia Vivarelli, Antonella Di Francesco, Emanuele Alpi, Nunzio Iraci, Rosaria Saletti   +10 more
wiley   +1 more source

Importance of Particle-Phase Reactions in the Growth of Newly Formed Particles. [PDF]

ACS Earth Space Chem
Vasudevan-Geetha V, Tiszenkel L, Wang Z, Russo R, Bryant DJ, Lee-Taylor J, Barsanti KC, Lee SH.   +7 more
europepmc   +1 more source

Nano-LC-orbitrap MS/MS-based quantitative proteomics and transpcriptomics for uncovering the mechanisms of action of rosemary bioactives in colon cancer: a new foodomics approach

, 2016
Resumen del trabajo presentado al 43rd Annual North American Meeting of the Federation of Analytical Chemistry and Spectroscopy Societies: "Great Scientific Exchange", celebrado en Minneapolis, Minnesota (USA) del 18 al 23 de septiembre de 2016. Recently, Foodomics has demonstrated to be a useful strategy to cover the identification of a wide range of ...
Valdés, Alberto, García-Cañas, Virginia, Artemenko, Konstantin A., Bergquist, Jonas, Cifuentes, Alejandro   +4 more
openaire   +1 more source