Results 191 to 200 of about 91,527 (300)

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng   +13 more
wiley   +1 more source

Design and commissioning of a new synchrotron beamline dedicated to X‐ray footprinting mass spectrometry

open access: yesJournal of Synchrotron Radiation, EarlyView.
A dedicated beamline at the Advanced Light Source synchrotron has been opened and commissioned for X‐ray footprinting mass spectrometry.The structural biology method of X‐ray footprinting mass spectrometry (XFMS) is available at two national synchrotron beamlines in the USA: one at the Advanced Light Source (ALS) on the West Coast and the other at the ...
Sayan Gupta   +19 more
wiley   +1 more source

Suspect Screening for PFAS in Groundwater with an Accessible LC-MS Workflow. [PDF]

open access: yesACS Omega
da Silva BF   +5 more
europepmc   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

open access: yesIntegrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang   +5 more
wiley   +1 more source

Integration of alternative fragmentation techniques into standard LC-MS workflows using a single deep learning model enhances proteome coverage. [PDF]

open access: yesNat Methods
Levin N   +8 more
europepmc   +1 more source

Gonadal Development–Related Genes and a Male‐Specific Genetic Marker Identified in the Endangered Sichuan Taimen (Hucho bleekeri)

open access: yesIntegrative Zoology, EarlyView.
Integrated transcriptomic and proteomic analyses were used to validate gonadal development–related genes and to identify a sex‐specific molecular marker in Hucho bleekeri. ABSTRACT Sex determination and differentiation represent fundamental topics in reproductive biology. Sichuan taimen (Hucho bleekeri), a first‐class national protected fish species in
Qinyao Wei   +5 more
wiley   +1 more source

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