Results 201 to 210 of about 91,527 (300)

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Multi-analytical dataset on Lekhaniya Mahakashaya: HRLC-MS/MS Orbitrap profiling, HPTLC fingerprinting with marker estimation, and FTIR spectroscopy. [PDF]

Data Brief
Singh N, Upadhyay A, Chakraborty D, Patil G, Yadav P, R G, Prajapati PK.   +6 more
europepmc   +1 more source

Tau phosphorylation rates measured by mass spectrometry differ in the intracellular brain vs. extracellular cerebrospinal fluid compartments and are differentially affected by Alzheimer’s disease [PDF]

, 2019
Barthelemy, Nicolas R, Bateman, Randall J, Mallipeddi, Nipun, Moiseyev, Paul, Sato, Chihiro   +4 more
core   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, EarlyView.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

Evaluation of a Prototype Orbitrap Astral Zoom Mass Spectrometer for Quantitative Proteomics─Beyond Identification Lists. [PDF]

J Proteome Res
Hsu C, Shulman N, Stewart HI, Petzoldt J, Pashkova A, Plubell DL, Denisov E, Hagedorn B, Damoc NE, MacLean BX, Remes PM, Canterbury JD, Makarov AA, Hock C, Zabrouskov V, Wu CC, MacCoss MJ.   +16 more
europepmc   +1 more source

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

Brain Pathology, EarlyView.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma, Robert Blair, Yao‐Zhong Liu, Xiaolei Wang, Eunice Vincent, Christopher Yu, Lara A. Doyle‐Meyers, Cissy Zhang, Ahmad Saied, Anne Le, Ronald S. Veazey, Qigui Yu, Huanbin Xu   +12 more
wiley   +1 more source

Paradigm Shift in Monoclonal Protein Detection: From Electrophoresis-based to Mass Spectrometry-based Methods. [PDF]

Ann Lab Med
Lee J, Yoo S, Yang S, Song SH.
europepmc   +1 more source

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida, Yuchen Sun, Noriaki Arakawa, Takuya Hirao, Tadahaya Mizuno, Shigeki Aoki, Kousei Ito, Yoshihiro Hayakawa   +7 more
wiley   +1 more source

Stable Nitrogen Isotope Analysis of Amino Acids by Orbitrap Mass Spectrometry: Application for Extraterrestrial Samples. [PDF]

Rapid Commun Mass Spectrom
McIntosh OM, Baczynski AA, Matney M, McLain HL, Farnsworth KK, Dworkin JP, Glavin DP, Elsila JE, Xie H, Freeman KH.   +9 more
europepmc   +1 more source

Sensitive quantification of BB-22 and its metabolite BB-22 3-carboxyindole, and characterization of new metabolites in authentic urine and/or serum specimens obtained from three individuals by LC-QTRAP-MS/MS and high-resolution LC-Orbitrap-MS/MS. [PDF]

Forensic Toxicol, 2019
Minakata K, Hasegawa K, Nozawa H, Yamagishi I, Saitoh T, Yoshino A, Suzuki M, Kitamoto T, Suzuki O, Watanabe K.   +9 more
europepmc   +1 more source