Results 11 to 20 of about 60,310 (255)

Analytical Characterization of 3-MeO-PCP and 3-MMC in Seized Products and Biosamples: The Role of LC-HRAM-Orbitrap-MS and Solid Deposition GC-FTIR

open access: yesFrontiers in Chemistry, 2021
Among the phencyclidine (PCP) and synthetic cathinone analogs present on the street market, 3-methoxyphencyclidine (3-MeO-PCP) is one of the most popular dissociative hallucinogen drugs, while 3-methylmethcathinone (3-MMC) is a commonly encountered ...
Giampietro Frison   +12 more
doaj   +1 more source

Public LC-Orbitrap-MS/MS Spectral Library for Metabolite Identification [PDF]

open access: yes, 2020
ABSTRACTLiquid chromatography-mass spectrometry(LC-MS)-based untargeted metabolomics studies require high-quality spectral libraries for reliable metabolite identification. We have constructed EMBL-MCF, an open LC-MS/MS spectral library that currently contains over 1600 fragmentation spectra from 435 authentic standards of endogenous metabolites and ...
Prasad Phapale   +5 more
openaire   +1 more source

Separation and quantification of imidazoles in atmospheric particles using LC–Orbitrap‐MS [PDF]

open access: yesJournal of Separation Science, 2019
AbstractA method using ultra‐high performance liquid chromatography coupled to a high resolution Orbitrap mass spectrometer was developed to identify and quantify imidazoles in aqueous extracts of aerosol particles. The aqueous particle extract was used without further enrichment or sample clean‐up.
Monique Teich   +4 more
openaire   +2 more sources

Screening of 258 Pesticide Residues in Silage Using Modified QuEChERS with Liquid- and Gas Chromatography-Quadrupole/Orbitrap Mass Spectrometry

open access: yesAgriculture, 2022
A method for the simultaneous screening of 258 pesticide residues in silage using modified QuEChERS combined with liquid chromatography (LC)- and gas chromatography (GC)- quadrupole-Orbitrap mass spectrometry (Q-Orbitrap/MS) has been developed.
Yujie Xie   +7 more
doaj   +1 more source

Improved LC−MS Method for the Determination of Fatty Acids in Red Blood Cells by LC−Orbitrap MS [PDF]

open access: yesAnalytical Chemistry, 2011
We report a new method for fast and sensitive analyses of biologically relevant fatty acids (FAs) in red blood cells (RBC) by liquid chromatography mass spectrometry (LC-MS). A new chemical derivatization approach was developed forming picolylamides from FAs in a quantitative reaction.
Xingnan, Li, Adrian A, Franke
openaire   +2 more sources

LC-ESI/LTQ-Orbitrap-MS Based Metabolomics in Evaluation of Bitter Taste of Arbutus unedo Honey

open access: yesMolecules, 2021
Strawberry tree honey is a high-value honey from the Mediterranean area and it is characterised by a typical bitter taste. To possibly identify the secondary metabolites responsible for the bitter taste, the honey was fractionated on a C18 column and the
Paola Montoro   +3 more
doaj   +1 more source

Metabolomics Benefits from Orbitrap GC–MS—Comparison of Low- and High-Resolution GC–MS

open access: yesMetabolites, 2020
The development of improved mass spectrometers and supporting computational tools is expected to enable the rapid annotation of whole metabolomes. Essential for the progress is the identification of strengths and weaknesses of novel instrumentation in ...
Daniel Stettin   +2 more
doaj   +1 more source

Development, Validation, and Comparison of Two Mass Spectrometry Methods (LC-MS/HRMS and LC-MS/MS) for the Quantification of Rituximab in Human Plasma

open access: yesMolecules, 2021
Rituximab is a chimeric immunoglobulin G1-kappa (IgG1κ) antibody targeting the CD20 antigen on B-lymphocytes. Its applications are various, such as for the treatment of chronic lymphoid leukemia or non-Hodgkin’s lymphoma in oncology, and it can also be ...
Aurélien Millet   +6 more
doaj   +1 more source

AMDORAP: Non-targeted metabolic profiling based on high-resolution LC-MS

open access: yesBMC Bioinformatics, 2011
Background Liquid chromatography-mass spectrometry (LC-MS) utilizing the high-resolution power of an orbitrap is an important analytical technique for both metabolomics and proteomics.
Ogasawara Naotake   +3 more
doaj   +1 more source

MS-H: a novel proteomic approach to isolate and type the E. coli H antigen using membrane filtration and liquid chromatography-tandem mass spectrometry (LC-MS/MS). [PDF]

open access: yesPLoS ONE, 2013
Serotyping is the long-standing gold standard method to determine E. coli H antigens; however, this method requires a panel of H-antigen specific antibodies and often culture-based induction of the H-antigen flagellar motility. In this study, a rapid and
Keding Cheng   +17 more
doaj   +1 more source

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