Olive Oil Quality and Authenticity Assessment Aspects Employing FIA-MRMS and LC-Orbitrap MS Metabolomic Approaches. [PDF]
Front Public Health, 2020 Edible vegetable oils comprise integral components of humans’ daily diet during the lifetime. Therefore, they constitute a central part of dietary-exposome, which among other factors regulates human health. In particular, the regular consumption of olive oil (OO) has been largely accepted as a healthy dietary pattern. Responsible for its recognition as
Nikou T +4 more
europepmc +6 more sources
Practical Protocol for Making Calibration Curves for Direct and Sensitive Quantitative LC Orbitrap-MS of Large Neuropeptides. [PDF]
Mass Spectrom (Tokyo), 2020 Peptides larger than 3-4 kDa, such as neuropeptide Y (NPY), orexin-B, and alpha-MSH, have practical issues that arise when conducting direct and sensitive quantitative liquid chromatography (LC) orbitrap-FT mass spectrometry (MS) due to their adsorption and low ionization efficiency, especially in standard solutions. A mixing solvent consisting of 0.5%
Yamagaki T, Yamazaki T.
europepmc +4 more sources
Screening of multi-class antibiotics in pork meat by LC-Orbitrap-MS with modified QuEChERS extraction. [PDF]
RSC Adv, 2019 The quantification capability of high resolution mass spectrometry is of great interest to analysts.
Chen Q +4 more
europepmc +4 more sources
Toxicometabolomics of lindane in adult zebrafish (Danio rerio) using GC-MS/MS and LC-Orbitrap-MS/MS [PDF]
Applied Biological Chemistry, 2021 AbstractLindane is a broad-spectrum persistent organochlorine pesticide that has been used to control pests for many years. In this study, its toxic mechanisms in adult zebrafish were investigated using targeted metabolomics with GC-MS/MS and non-targeted metabolomics with LC-Orbitrap-MS/MS.
Xiu Yuan +4 more
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Public LC-Orbitrap-MS/MS Spectral Library for Metabolite Identification [PDF]
, 2020 ABSTRACTLiquid chromatography-mass spectrometry(LC-MS)-based untargeted metabolomics studies require high-quality spectral libraries for reliable metabolite identification. We have constructed EMBL-MCF, an open LC-MS/MS spectral library that currently contains over 1600 fragmentation spectra from 435 authentic standards of endogenous metabolites and ...
Prasad Phapale +5 more
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Separation and quantification of imidazoles in atmospheric particles using LC–Orbitrap‐MS [PDF]
Journal of Separation Science, 2019 AbstractA method using ultra‐high performance liquid chromatography coupled to a high resolution Orbitrap mass spectrometer was developed to identify and quantify imidazoles in aqueous extracts of aerosol particles. The aqueous particle extract was used without further enrichment or sample clean‐up.
Monique Teich +4 more
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Determination of Cotinine, 3'-Hydroxycotinine and Nicotine 1'-Oxide in Urine of Passive and Active Young Smokers by LC-Orbitrap-MS/MS Technique. [PDF]
MoleculesTobacco smoke is probably the most significant factor conducing to toxic xenobiotics exposure to humans. The aim of the study was to develop a rapid and sensitive method for the determination of selected nicotine metabolites in urine of tobacco smokers and passive smokers.
Szumska M +4 more
europepmc +4 more sources
Improved LC−MS Method for the Determination of Fatty Acids in Red Blood Cells by LC−Orbitrap MS [PDF]
Analytical Chemistry, 2011 We report a new method for fast and sensitive analyses of biologically relevant fatty acids (FAs) in red blood cells (RBC) by liquid chromatography mass spectrometry (LC-MS). A new chemical derivatization approach was developed forming picolylamides from FAs in a quantitative reaction.
Xingnan, Li, Adrian A, Franke
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An Efficient Workflow for Quality Control Marker Screening and Metabolite Discovery in Dietary Herbs by LC-Orbitrap-MS/MS and Chemometric Methods: A Case Study of Chrysanthemum Flowers. [PDF]
FoodsLC-MS is widely utilized in identifying and tracing plant-derived food varieties but quality control markers screening and accurate identification remain challenging. The adulteration and confusion of Chrysanthemum flowers highlight the need for robust quality control markers.
Yuan H +6 more
europepmc +4 more sources
Evaluation and Optimization of Mass Spectrometric Settings during Data-dependent Acquisition Mode: Focus on LTQ-Orbitrap Mass Analyzers [PDF]
, 2013 Mass-spectrometry-based proteomics has evolved as the preferred method for the analysis of complex proteomes. Undoubtedly, recent advances in mass spectrometry instrumentation have greatly enhanced proteomic analysis.
Hess, Sonja +3 more
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