Results 261 to 270 of about 313,222 (315)

Study the influence of licorice and pomegranate drinks on nicotine metabolism in human urine by LC-orbitrap MS

Journal of Pharmaceutical and Biomedical Analysis, 2017
Nicotine-diet interactions have a particular importance on human health. Some food substances are subject to change hepatic CYP2A6 metabolism rate for nicotine and its levels in smokers consequently. This study investigates the effect of pomegranate and licorice drinks on nicotine metabolism, by a new developed and validated method for simultaneous ...
Ahmad Abu-awwad, Tawfiq Arafat, Oliver J. Schmitz   +2 more
openaire   +4 more sources

Chemical profiling and comparative analysis of different parts of Asarum heterotropoides using SPME-GC-QTOF-MS and LC- Orbitrap -MS

Journal of Pharmaceutical and Biomedical Analysis
Asari radix et rhizoma is the sole plant from the Aristolochiaceae family officially sanctioned for medicinal in China, primarily employed for treating colds and headaches, and is widely utilized in clinical practice. Initially, the entire plant was specified for medicinal use, but since 2005, the authorized part has been restricted to the roots and ...
Yun-Shu, Hu, Jian-Qing, Zhang, Meng, Xu, Huan-Ya, Yang, Chun-Xiang, Liu, Yun, Li, Qi-Rui, Bi, Yang, Yang, Qin-Hua, Chen, De-An, Guo   +9 more
openaire   +3 more sources

Quantifying vitamin D and its metabolites by LC/Orbitrap MS

Analytical Methods, 2015
We developed a HPLC-HRMS method for the determination of 25(OH)D2, 25(OH)D3, epi-25(OH)D3, and vitamins D2and D3as well as 24,25(OH)2D3.
Reingard Raml, Maria Ratzer, Barbara Obermayer-Pietsch, Anton Mautner, Thomas R. Pieber, Frank M. Sinner, Christoph Magnes   +6 more
openaire   +2 more sources

Simultaneous determination of nicotine, cotinine, and nicotine N-oxide in human plasma, semen, and sperm by LC-Orbitrap MS

Analytical and Bioanalytical Chemistry, 2016
Nicotine (Nic) distribution in human fluids and tissues has a deleterious effect on human health. In addition to its poisoning profile, Nic may contribute to the particular impact of smoking on human reproduction. Although present in seminal fluid, still nobody knows whether nicotine is available in sperm or not.
Abu-Awwad, Ahmad, Arafat, Tawfiq, Schmitz, Oliver J.   +2 more
openaire   +3 more sources

The use of LC-Orbitrap MS for the detection of Fusarium masked mycotoxins: the case of type A trichothecenes

World Mycotoxin Journal, 2012
‘Masked mycotoxins’ (mycotoxin glucosides) derived from type A trichothecenes (T-2 toxin and HT-2 toxin) were detected in commercially available maize powder reference material. These novel glucosides were identified as T-2 toxin-glucoside (T2-Glc) and HT-2 toxin-glucoside (HT2-Glc) on the basis of accurate mass measurements of characteristic ions and ...
H. Nakagawa, S. Sakamoto, Y. Sago, M. Kushiro, H. Nagashima   +4 more
openaire   +2 more sources

LC-Orbitrap MS analysis of the glycation modification effects of ovalbumin during freeze-drying with three reducing sugar additives

Food Chemistry, 2018
In general, the reducing sugars were extensively utilized as additives to prevent denaturation and inactivation during the freeze-drying process. However, different additives have unequal protective effects on the protein conformation. To evaluate the mechanism of protection the protein structure using different additives in the freeze-drying process ...
Yang Chen, Zong-cai Tu, Hui Wang, Guang-xian Liu, Zi-wei Liao, Lu Zhang   +5 more
openaire   +3 more sources

Extraction optimization and screening of angiotensin-converting enzyme inhibitory peptides from Channa striatus through bioaffinity ultrafiltration coupled with LC-Orbitrap-MS/MS and molecular docking.

Food Chemistry, 2021
Channa striatus is high-protein food with many health functions. This study aimed to prepare, screen and identify the angiotensin-converting enzyme inhibition peptides (ACEIPs) from C. striatus hydrolysates by response surface methodology and bioaffinity
Tian-xin Ma, Qiaoqin Fu, Qianggen Mei, Z. Tu, Lu Zhang   +4 more
semanticscholar   +1 more source

Identification and characterization of the metabolites of moscatilin in mouse, rat, dog, monkey and human hepatocytes by LC-Orbitrap-MS/MS combined with diagnostic fragment ions and accurate mass measurements.

Biomedical chromotography, 2022
Moscatilin, a bibenzyl derivative from the stem of Dendrobium loddigesii, has been shown to have anticancer activity. The aim of this study was to identify and characterize the possible in vitro metabolites of moscatilin generated from hepatocytes.
Aizhen Hu, Qingwang Liu, J. Ouyang
semanticscholar   +1 more source

Determination of illicit drugs in the water cycle by LC-Orbitrap MS

2011
de Voogt, P., Emke, E., Helmus, R., Panteliadis, P., van Leerdam, J.A.   +4 more
openaire   +3 more sources

Investigation of the mechanism underlying the influence of mild glycation on the digestibility and IgG/IgE-binding abilities of β-lactoglobulin and its digests through LC orbitrap MS/MS

LWT, 2020
This study aimed to investigate the mechanism underlying the influence of mild glycation on the digestibility and anaphylactic effect of β-lactoglobulin (βLG) and its digests through LC Orbitrap MS/MS. Three glycated sites were discovered after glycation
Wang Xumei, Y. Ye, Z. Tu, Yue‐ming Hu, Hui Wang, Cheng-yan He   +5 more
semanticscholar   +1 more source