Results 231 to 240 of about 101,793 (284)

Measuring cytotoxicity: a new perspective on LC50.

Anticancer research, 2007
Cytotoxicity in cell culture is typically expressed as LC50 the concentration of a given agent which is lethal to 50% of the cells. This number is dependent on the incubation time with the agent. Previously, a two-term exponential model has been proposed to describe cell growth after a cytotoxic event: y(t) = k, * exp(-d(1)*t) + k2 * exp(d(2)*t).
Ming, Zhang, Dolly, Aguilera, Chandra, Das, Hernan, Vasquez, Peter, Zage, Vidya, Gopalakrishnan, Johannes, Wolff   +6 more
openaire   +1 more source

Dependence between LD50 for Rodents and LC50 for Adult Fish and Fish Embryos

Bulletin of Experimental Biology and Medicine, 2017
We revealed empirical dependences between common logarithm of a ratio of rat oral LD50 to LCa50 for adult fish and lgP for 50 different chemicals; and common logarithm of a ratio of the oral LD50 in rodents to LCe50 for fish embryos and lgP for 30 different chemicals.
K V, Zolotarev, N F, Belyaeva, A N, Mikhailov, M V, Mikhailova   +3 more
openaire   +2 more sources

The utility of computed superdelocalizability for predicting the LC50 values of epoxides to guppies

Science of The Total Environment, 1991
A quantitative structure-activity relationship (QSAR) was found for predicting the pseudo-first-order reaction rate constant of the alkylating chemical 4-nitrobenzylpyridine with a set of epoxides. The superdelocalizability of the unoccupied levels of the orbital along the carbon-oxygen bond of the least substituted carbon was found to be an excellent ...
openaire   +2 more sources

Standard error of lc50 and sample size in fish bioassays

Water Research, 1972
Abstract The relationship between the relative error and sample size in fish bioassays was investigated empirically and theoretically. It was shown that if the mean concentration tested is near the estimated lc 50 and the same sample size is used at each test level, the dependence of relative error on sample size is predictable.
openaire   +1 more source

LC50 Value of Paraquat (24%) in Drosophila Melanogaster Larvae

BIOINFOLET - A Quarterly Journal of Life Sciences
AbstractThe objective of present investigation was to determine the Lethal Concentration 50 (LC50) of commercially available paraquat. a herbicide, at 24 % dilution with second instar larvae of Drosophila melanogaster. For this purpose the second instar larvae, were exposed to different concentrations of paraquat (20, 22, 24, 26 and 28 µl/ml ...
Girima Nagda, Chhavi Bhalothia
openaire   +1 more source

LC50

2008
Laura T. Miller, Lionel Stange, Charles MacVean, Jorge R. Rey, J. H. Frank, R. F. Mizell, John B. Heppner, John B. Heppner, John L. Capinera, Dorothy Feir, Christian Borgemeister, George Hangay, R. Wills Flowers, John B. Heppner, Klaus Jaffe, Chris H. Dietrich, Stéphanie Boucher, John B. Heppner, Whitney Cranshaw, Whitney Cranshaw, John B. Heppner, Spencer T. Behmer, Fred Punzo, Drion Boucias, Severiano F. Gayubo, Peter E. Kima, Yousif Aldryhim, John L. Capinera, Diane M. Calabrese, John B. Heppner, James L. Nation, Dan M. Harman, John B. Heppner, Qiao Wang, Marc A. A. Pollet, Scott E. Brooks, John B. Heppner, Norman C. Leppla, Douglas E. Norris, John B. Heppner   +39 more
openaire   +2 more sources

Acute LC50 Value of Methotrexate in Drosophila Melanogaster Larvae

BIOINFOLET - A Quarterly Journal of Life Sciences
AbstractThe value of LC50 of the commercially available immunosuppressive drug methotrexate (MTX) was determined using the larvae of Drosophila melanogaster. For this purpose, third instar larvae were exposed to different concentrations of MTX (75, 100, 150, 200 and 250 ppm). Probit analysis was done on the dose-response data in order to find LC50. The
Payal Patel, Girima Nagda
openaire   +1 more source

96 h LC50, behavioural alterations and histopathological effects due to wastewater toxicity in a freshwater fish Channa punctatus

Environmental science and pollution research international, 2015
Rajbir Kaur, A. Dua
semanticscholar   +1 more source

Incorporating variability in point estimates in risk assessment: Bridging the gap between LC50 and population endpoints

Environmental Toxicology and Chemistry, 2015
J. Stark, R. Vargas, J. Banks
semanticscholar   +1 more source

Introduction of moribund category to OECD fish acute test and its effect on suffering and LC50 values

Environmental Toxicology and Chemistry, 2012
H. Rufli
semanticscholar   +1 more source