Results 11 to 20 of about 193,846 (93)
The interaction between LC8 and LCA5 reveals a novel oligomerization function of LC8 in the ciliary-centrosome system [PDF]
, 2022 Dynein light chain LC8 is a small dimeric hub protein that recognizes its partners through short linear motifs and is commonly assumed to drive their dimerization. It has more than 100 known binding partners involved in a wide range of cellular processes.
Fülöp, Máté +7 more
core +1 more source
Elucidating the Roles of LC8 Binding
LC8 binding was explored through its interactions with the disordered transcription factor ASCIZ. ASCIZ was chosen as a model as it is multivalent, containing many different types of LC8 binding motifs as well as differing linker lengths between them ...
Fujimura, Gretchen M.
core +6 more sources
Regulation of 53BP1 Binding to LC8 Through Phosphorylation
The tumor-suppressor p53 binding protein 1 (53BP1) is a crucial component of the DNA damage response and prevention of cancer development. The structure of 53BP1 includes an oligomerization domain (OD) in addition to a dynein light chain 8 (LC8) binding ...
Sonpatki, Maya
core +6 more sources
, 2019 International audienceThe rabies and Ebola viruses recruit the highly conserved host protein LC8 for their own reproductive success. in vivo knockouts of the LC8 recognition motif within the rabies virus phosphoprotein (RavP) result in completely non ...
Jespersen, Nathan +6 more
core +2 more sources
LC8 binding peptides interact with endogenous LC8.
, 2013 (a) Overexpression of WTY-2 -GFP tagged peptide prevents the localization of FS-PEG-WTY-2. (b) Overexpression of Mut2G0-GFP tagged peptide does not affect FS-PEG-WTY-2 localization. Oocytes are shown 45 min after injection.
Nadège Parassol (496406) +11 more
core +1 more source
Ranges for thermodynamic parameters for LC8-client binding when modeled with ±20% LC8 concentration.
, 2023 Table 1 in the main text contains equivalent information at ±10% LC8 concentration. Values delineate 95% Bayesian credibility regions from sampled posterior distributions, when modeled with ±20% priors for LC8 concentration.
Daniel M. Zuckerman (1325964) +3 more
core +1 more source
Enhancing Online Teaching of Business Statistics: A Pedagogy Before Technology Approach
International Review of Research in Open and Distributed LearningLearning statistics can be challenging for many students, due to their inability to engage in statistical reasoning and application of techniques. This challenge becomes compounded in online learning contexts where students are spatially and temporally ...
Bopelo Boitshwarelo, Maneka Jayasinghe
doaj +1 more source
LC8 binds clients through a two-site mechanism.
, 2023 (a) Diagram of LC8-client binding, showing a structure of apo LC8 on the left, and a fully bound structure (PDB 3E2B) on the right. Intermediates are boxed to indicate they are symmetric and indistinguishable species.
Daniel M. Zuckerman (1325964) +3 more
core +1 more source
Empowering Asynchronous Arabic Language Learning Through PDF Hyperlink Media
International Review of Research in Open and Distributed LearningThe migration to online learning has brought about several new problems. Poor signal quality, large Internet quotas, and device compatibility with learning applications are the most common complaints among students.
Agus Riwanda +2 more
doaj +1 more source