Curvilinear relationship between life's crucial 9 and metabolic syndrome in U.S. adults: a cross-sectional study [PDF]
BackgroundMetabolic Syndrome (MetS) is closely linked to cardiovascular disease. However, no studies have examined the relationship between Life’s Crucial 9 (LC9) and MetS.
Bo Wang +6 more
doaj +2 more sources
The mediating role of Body Roundness Index in the association between Life’s Crucial 9 and infertility: a cross-sectional study using NHANES 2013–2018 [PDF]
BackgroundRecent findings indicate a possible connection among heart health, obesity, and infertility. Yet, the processes through which obesity affects the link between heart health and infertility are still not well-understood.
Ying Wang +5 more
doaj +2 more sources
Quantifying the association of Life’s Crucial 9 with cardiovascular diseases among elderly hypertensive patients managed in primary care settings [PDF]
Background Life’s Crucial 9 (LC9), an extension for Life’s Essential 8 with the addition of psychological health, provides a new tool for assessing cardiovascular health.
Lipei Zhao +8 more
doaj +2 more sources
Neutrophil-to-albumin ratio mediates the association between Life’s Crucial 9 and chronic obstructive pulmonary disease [PDF]
BackgroundChronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and chronic airway inflammation.
Jing Feng, Hongyang Gong
doaj +2 more sources
Association of Life’s Crucial 9 with cognitive function and stroke risk: insights from the NHANES 2011–2014 study [PDF]
Background Cognitive impairment and stroke constitute major health challenges for the aging global population, adversely impacting quality of life and increasing healthcare burdens.
Renjie Liu +3 more
doaj +2 more sources
Association between life’s crucial 9 and major eye diseases among US adults aged 40 years or older [PDF]
Background Vision impairment due to eye diseases represents a significant global public health concern. There is an increasing acknowledgment of the relationship between cardiovascular health (CVH) and eye diseases.
Yang Meng +6 more
doaj +2 more sources
Utilizing Life's Crucial 9 for Rheumatoid Arthritis Risk Prediction: A Machine Learning Approach Based on NHANES Data. [PDF]
This study based on NHANES 2011–2018 (16,154 adults) found that higher LC9 score is an independent protective factor for rheumatoid arthritis (RA), with each 1‐unit increase associated with a 27% lower risk (OR = 0.73). An XGBoost machine learning model integrating LC9 and clinical covariates achieved excellent predictive performance (test AUC = 0.987).
Zheng J +6 more
europepmc +2 more sources
Background Cardiovascular health (CVH) is a key determinant of mortality, but the comparative effectiveness of different CVH metrics remains uncertain.
Xu Zhu +8 more
doaj +2 more sources
BackgroundPsoriasis is a chronic, recurrent, inflammatory disease. The aim of this study was to investigate the association between the Life’s Crucial 9 (LC9) score and the risk of psoriasis and to examine the mediating role of system inflammation ...
Xinyan Liu, Qirui Deng, Hongfeng Tang
exaly +3 more sources
Association of life’s crucial 9 score with benign prostatic hyperplasia: a cross-sectional study [PDF]
Background Benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are prevalent prostate diseases in aging male populations, with significant implications for quality of life and healthcare burden.
Haoran Wang +6 more
doaj +2 more sources

