Results 201 to 210 of about 251,423 (287)

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

Timed exercise modulates inter-coupling strength between evening and morning oscillators in mice. [PDF]

NPJ Biol Timing Sleep
Miyagi N, Matsuura N, Yamanaka Y.
europepmc   +1 more source

LD&C possibilities for the next decade

, 2017
Nick Thieberger
openalex   +1 more source

IN THE MATTER OF AN APPLICATION BY WILLIAM BAILEY (BIRMINGHAM) LD. TO REGISTER A TRADE MARK AND IN THE MATTER OF AN OPPOSITION THERETO BY A. C. GILBERT CO. [PDF]

, 1935

openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Red and blue laser light drives photosynthesis through dynamic changes of stomatal aperture. [PDF]

Front Plant Sci
Yoshi K, Takahashi M, Negishi M.
europepmc   +1 more source

J. C. & J. FIELD, LD.V.WAGEL SYNDICATE, LD., AND IN THE MATTER OF TRADE MARK NO. 96,997 (“SAVONOL”) [PDF]

, 1900

openalex   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid-Induced Neurotoxic Phenotype of Astrocytes. [PDF]

Glia
Esteve D, Bresque M, Okhuevbie D, Ramachandran S, Pehar M, Vargas MR.   +5 more
europepmc   +1 more source

Likelihood ratio para trisomía 21 en fetos con regurgitación tricuspídea en ecografía entre las 11 y 13 + 6 semanas (1) Faiola S, Tsoi E, Huggon C, Allan LD, Nicolaides KH. Ultrasound Obstet Gynecol 2005; 26: 22-27 [PDF]

, 2005
Manuel Schepeler S., Claudio Vera P-G, Jorge Carvajal C   +2 more
openalex   +1 more source