Testosterone enhances Aβ‐induced autophagy in microglia via the non‐genomic testosterone receptor GPRC6A, promoting Aβ clearance by suppressing ERK phosphorylation and inhibiting mTOR activation. In male 5xFAD mice, testicular removal reduces microglial autophagy and Aβ clearance, which is restored by testosterone.
Haiyan Du+8 more
wiley +1 more source
Effects of different rearing systems on the development of uropygial gland in three goose breeds. [PDF]
Hu S+9 more
europepmc +1 more source
Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites. [PDF]
Bezawork-Geleta A+19 more
europepmc +1 more source
Improved jet lag recovery is associated with a weaker molecular biological clock response around the time of expected activity onset. [PDF]
Boutrin MC+3 more
europepmc +1 more source
Age-related changes in the cytoplasmic ultrastructure of feline oocytes. [PDF]
Natalia B+7 more
europepmc +1 more source
Lipid droplet efferocytosis attenuates proinflammatory signaling in macrophages via TREM2- and MS4A7-dependent mechanisms. [PDF]
Zhou L+9 more
europepmc +1 more source
Efficacy comparison of two doses of dezocine on preventing sufentanil-induced cough in patients undergoing coronary artery bypass grafting surgery: A prospective, randomized controlled trial. [PDF]
Xie CM+4 more
europepmc +1 more source
Organization of the Yeast Seipin Complex Reveals Differential Recruitment of Regulatory Proteins
Klug YA, Carvalho P.
europepmc +1 more source